(4-Chloro-3-ethoxyphenyl) - Names and Identifiers
(4-Chloro-3-ethoxyphenyl) - Physico-chemical Properties
Molecular Formula | C8H10BClO3
|
Molar Mass | 200.43 |
Storage Condition | Inert atmosphere,2-8°C |
(4-Chloro-3-ethoxyphenyl) - Introduction
Boronic acid, (4-chloro-3-ethoxyphenyl)-is an organic compound with the chemical formula C8H9BClO2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White solid
-Melting point: about 150-151°C
-Solubility: It is soluble in some organic solvents, such as ethanol, dichloromethane and dimethyl sulfoxide.
Use:
- Boronic acid, (4-chloroo-3-ethoxyphenyl)-is widely used in organic synthesis reactions, especially in coupling reactions, such as palladium-catalyzed Suzuki coupling and Suzuki-Miyaura coupling reactions.
-It can also be used as a ligand for the synthesis of metal complexes.
Method:
- Boronic acid, (4-chloro-3-ethoxyphenyl)-can be obtained by reacting phenylboronic acid with the corresponding chlorinated alkyl compound or alkyl bromide.
-The specific preparation method can be reacting phenylboronic acid with 4-chloro-3-ethoxyphenylsulfonyl chloride under the catalysis of a base.
Safety Information:
- Boronic acid, (4-chloroo-3-ethoxyphenyl)-is generally stable under normal operating conditions.
-But it is a chemical substance, you need to pay attention to safe operation and avoid contact with skin and eyes.
-It may have potential health hazards to the human body, such as irritation and inhalation risk.
-When using, you must follow the relevant laboratory safety procedures and be equipped with appropriate personal protective equipment.
Last Update:2024-04-10 22:29:15