(4E,7E,10Z,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenoic acid
cis-4,7,10,13,16,19-docosahexaenoic acid
CAS: 6217-54-5;25167-62-8
Molecular Formula: C22H32O2
(4E,7E,10Z,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenoic acid - Names and Identifiers
(4E,7E,10Z,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenoic acid - Physico-chemical Properties
| Molecular Formula | C22H32O2 |
| Molar Mass | 328.49 |
| Density | 0.943±0.06 g/cm3(Predicted) |
| Melting Point | -44°C |
| Boling Point | 446.7±24.0 °C(Predicted) |
| Flash Point | 62°C |
| Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated, Son |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | A colored transparent liquid |
| Color | Clear colorless to light yellow |
| Merck | 14,3398 |
| BRN | 1715505 |
| pKa | 4.58±0.10(Predicted) |
| Storage Condition | -20°C |
| Stability | Light and Air Sensitive |
| Sensitive | Sensitivity to air, light and heat |
| Refractive Index | 1.5030-1.5060 |
| MDL | MFCD00065722 |
(4E,7E,10Z,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenoic acid - Risk and Safety
| Safety Description | S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. |
| UN IDs | UN1170 - class 3 - PG 2 - Ethanol, solution |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-10-23 |
| HS Code | 29161900 |
(4E,7E,10Z,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenoic acid - Reference
| Reference Show more | 1. Xu, Huang, Yi, Xin, Jiang, et al. Effects of sodium selenite on DHA-mediated lipid metabolism in LPS-induced macrophages [J]. Chinese Journal of Veterinary Medicine 2020 v.40;No.281(05):160-165 171. 2. Xu Yi-yu, Huang Yi-xin, Luo Zhong-Xiong, etc. Selenium enhances the anti-inflammatory effect of dicarboxuhexaenoic acid on lipopolysaccharide-induced inflammatory response in macrophages [J]. Chinese Journal of Animal Nutrition, 2017(10). 3. [IF = 9.147] Ling Huang et al."Medical fatty acid-mediated protein encapsulation" absorption of astaxanthin."Food Hydrocolloid. 2022 Feb;123:107152 4. [IF=4.556] Jianlou Mu et al."Identification of the fatty acids profiles in supercritical CO2 fluid and Soxhlet extraction of Samara oil from different cultivars of Elaeagnus mollis Diels seeds."J Food Compos Anal. 2021 Aug;101:103982 |
(4E,7E,10Z,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenoic acid - Introduction
DHA is an essential fatty acid, which is the most abundant omega -3 fatty acid in nerve tissue, especially in the retina and brain. DHA constitutes a pool of polyunsaturated fatty acids up to 40% of retinal and nerve cell membranes. The use of fish oil DHA dietary supplements can inhibit atherosclerosis and delay the progress of retinitis pigmentosa with photoreceptor degeneration. DHA deficiency in newborns can lead to developmental defects, and DHA deficiency in rats may lead to hypertension.
Last Update：2024-04-10 22:29:15
(4E,7E,10Z,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenoic acid - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | docosahexaenoic acid (DHA) is an unsaturated fatty acid, which cannot be synthesized in human body and can only be ingested from food, is an essential fatty acid. It is an indispensable component for the development and function maintenance of brain and nervous tissue, and is found in a large number of brain cells in the human body. |
| trait | colorless liquid |
| properties | twenty-two carbon hexenoic acid is colorless to light yellow transparent liquid, pure odor-free, tasteless. Twenty-two-hexaenoic acid is composed of n3 series polyunsaturated fatty acids. |
| Use | Nutrition Fortifier. Nutrition Fortifier. is to promote brain development and enhance memory in infants and young children. DHA is the main component of fatty acids in the gray matter of the brain, the lack of which will affect mental development. Therefore, it is mainly to promote the brain development of infants and young children and prevent the brain atrophy and aging in the elderly. DHA is one of the most basic components of the human brain nervous system, the content of about 15% in the brain tissue, around 60% of the visual rod cells in the retina are DHA phospholipid molecules. Because DHA has a role in the transmission of signals between brain nerve cells, related memory and thinking function depends on the maintenance and improvement of DHA. Since the ratio of DHA to EPA in breast milk is 4:1, this makes the hydrolysis, absorption and utilization of DHA best. |
| usage limit | GB 2760-2002(g/kg): infant formula 0.4~1.8 (from dinoflagellates and tuna oil). Maternal milk powder 0.3~0.5 (from tuna oil). Infant formula 0.09% ~ 0.15% [percentage of total fatty acids; Refers to the single cell oil of two carbon acid (DHASCO)]. |
Last Update：2024-04-09 20:45:29
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