(5-Bromo-Pyridin-3-Yl)-Carbamic Acid Tert-Butyl Ester

(5-Bromo-Pyridin-3-Yl)-Carbamic Acid Tert-Butyl Ester - Names and Identifiers

Name	tert-butyl (5-bromopyridin-3-yl)carbamate
Synonyms	5-(Boc-amino)-3-bromopyridine 3-(Boc-amino)-5-bromopyridine 5-Bromo-3-(Boc-amino)-pyridine tert-Butyl 5-bromopyridine-3-carbamate tert-butyl 5-bromopyridin-3-ylcarbamate TERT-BUTYL 5-BROMOPYRIDIN-3-YLCARBAMATE tert-Butyl[5-bromopyridin-3-yl] carbamate tert-Butyl (5-bromopyridin-3-yl)carbamate tert-butyl (5-bromopyridin-3-yl)carbamate tert-Butyl N-(5-broMopyridin-3-yl)carbaMate (5-BROMO-PYRIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER (5-Bromo-Pyridin-3-Yl)-Carbamic Acid Tert-Butyl Ester Carbamic acid, (5-bromo-3-pyridinyl)-, 1,1-dimethylethyl ester
CAS	361550-43-8
InChI	InChI=1/C10H13BrN2O2/c1-10(2,3)15-9(14)13-8-4-7(11)5-12-6-8/h4-6H,1-3H3,(H,13,14)

(5-Bromo-Pyridin-3-Yl)-Carbamic Acid Tert-Butyl Ester - Physico-chemical Properties

Molecular Formula	C10H13BrN2O2
Molar Mass	273.13
Density	1.453g/cm³
Melting Point	143-148°C
Boling Point	286.5°C at 760 mmHg
Flash Point	127.1°C
Vapor Presure	0.00262mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.573

(5-Bromo-Pyridin-3-Yl)-Carbamic Acid Tert-Butyl Ester - Risk and Safety

Risk Codes	22 - Harmful if swallowed
WGK Germany	3
Hazard Class	IRRITANT

(5-Bromo-Pyridin-3-Yl)-Carbamic Acid Tert-Butyl Ester - Introduction

tert-butyl (5-bromopyridin-3-yl)carbamate is an organic compound whose chemical formula is C11H15BrN2O2.

Nature:
The compound is colorless to yellow crystals with a special odor. It has a melting point of about 98-99°C.

Use:
tert-butyl (5-bromopyridin-3-yl)carbamate is often used as an intermediate in organic synthesis and has important applications in the field of medicine and pesticide research and development. It can be used to synthesize a variety of organic compounds, such as pyridine derivatives and carbonyl compounds.

Preparation Method:
A common preparation method is generated by reacting tert-butylamine with 5-bromo-3-pyridinecarboxylic acid. The specific steps are as follows: First, in an appropriate solvent, tert-butylamine and 5-bromo-3-pyridinecarboxylic acid are heated and stirred to react to generate the target product. Then, a pure tert-butyl (5-bromopyridin-3-yl)carbamate is obtained by crystallization or other purification methods.

Safety Information:
There is limited information on the safety of this compound, so care should be taken in handling and use. Because it belongs to organic bromide, it has certain toxicity, so in the process of operation should pay attention to avoid contact with skin and eyes. At the same time, care should be taken to maintain good ventilation conditions and take appropriate personal protective measures, such as wearing protective gloves and goggles.

Last Update：2024-04-09 21:54:55