(5-Chloro-6-propoxypyridin-3-yl)boronic acid
(5-Chloro-6-propoxypyridin-3-yl)boronic acid
CAS: 1150114-70-7
Molecular Formula: C8H11BClNO3
(5-Chloro-6-propoxypyridin-3-yl)boronic acid - Names and Identifiers
(5-Chloro-6-propoxypyridin-3-yl)boronic acid - Physico-chemical Properties
| Molecular Formula | C8H11BClNO3 |
| Molar Mass | 215.44 |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD12025984 |
(5-Chloro-6-propoxypyridin-3-yl)boronic acid - Introduction
boronic acid is an organic boron compound with the chemical formula C10H12BNO3Cl. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or light yellow crystal
-Melting point: about 160-163°C
-Solubility: Soluble in some organic solvents, such as ethanol, dimethyl sulfoxide
Use:
(br) boronic acid is commonly used in boronation reactions in organic synthesis, mainly used as a donor of borate esters, participating in Suzuki coupling reactions, Negishi coupling reactions, etc. These reactions have important applications in medicinal chemistry, pesticide synthesis and materials science.
Preparation Method:
(Boron) boronic acid can be synthesized by a variety of synthetic routes. One common method is to react 5-chloro-6-propoxy pyridine with triethyl alkane under the catalysis of cuprous chloride to generate the target product.
Safety Information:
Although there is no specific safety data report, general organic boron compounds have certain toxicity and irritation. Therefore, in the use and handling, should follow the laboratory safety procedures, and take safety measures, such as wearing protective glasses and gloves, to avoid inhalation, contact with the skin or swallowing. In the event of an accident, medical help should be sought immediately.
Nature:
-Appearance: colorless or light yellow crystal
-Melting point: about 160-163°C
-Solubility: Soluble in some organic solvents, such as ethanol, dimethyl sulfoxide
Use:
(br) boronic acid is commonly used in boronation reactions in organic synthesis, mainly used as a donor of borate esters, participating in Suzuki coupling reactions, Negishi coupling reactions, etc. These reactions have important applications in medicinal chemistry, pesticide synthesis and materials science.
Preparation Method:
(Boron) boronic acid can be synthesized by a variety of synthetic routes. One common method is to react 5-chloro-6-propoxy pyridine with triethyl alkane under the catalysis of cuprous chloride to generate the target product.
Safety Information:
Although there is no specific safety data report, general organic boron compounds have certain toxicity and irritation. Therefore, in the use and handling, should follow the laboratory safety procedures, and take safety measures, such as wearing protective glasses and gloves, to avoid inhalation, contact with the skin or swallowing. In the event of an accident, medical help should be sought immediately.
Last Update：2024-04-09 20:49:11
