(5-Chloropyridin-2-yl)boronic acid

(5-Chloropyridin-2-yl)boronic acid - Names and Identifiers

Name	5-Chloropyridine-2-boronic acid
Synonyms	2-Borono-5-chloropyridine 5-Chloropyridine-2-Boronic 5-Chloro-2-pyridineboronicacid 5-Chloropyridine-2-BoronicAcid 5-CHLORO-2-PYRIDINEBORONIC ACID 5-CHLOROPYRIDINE-2-BORONIC ACID 5-Chloropyridine-2-boronic acid 5-Chloropyridin-2-ylboronic acid (5-Chloropyridin-2-yl)boronic acid acide (5-chloropyridin-2-yl)boronique Boronic acid, B-(5-chloro-2-pyridinyl)- Boronic acid, (5-chloro-2-pyridinyl)- (9CI)
CAS	652148-91-9
InChI	InChI=1/C5H5BClNO2/c7-4-1-2-5(6(9)10)8-3-4/h1-3,9-10H

(5-Chloropyridin-2-yl)boronic acid - Physico-chemical Properties

Molecular Formula	C5H5BClNO2
Molar Mass	157.36
Density	1.41±0.1 g/cm3(Predicted)
Boling Point	317.7±52.0 °C(Predicted)
Flash Point	145.9°C
Vapor Presure	0.000159mmHg at 25°C
pKa	7.66±0.53(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.559

(5-Chloropyridin-2-yl)boronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
Hazard Class	IRRITANT

(5-Chloropyridin-2-yl)boronic acid - Introduction

5-Chloropyridine-2-boronic acid is an organic compound with the formula C5H4BClNO2. It is a white solid crystal, soluble in some organic solvents such as dimethylthiourea and alcohol solvents.

5-Chloropyridine-2-boronic acid has a wide range of applications in organic synthesis. It can be used as an important intermediate in organic synthesis, for the synthesis of various natural products, drugs and pesticides and other organic compounds. It can participate in various reactions such as addition reactions, coupling reactions, and reduction reactions.

There are two main methods for preparing 5-Chloropyridine-2-boronic acid. One is obtained by the hydrogenation reduction reaction of 5-chloro-2-pyridone. The other is prepared by the reaction of 5-chloro-2-pyridone with boric acid.

Some safety information is required when using 5-Chloropyridine-2-boronic acid. It can be harmful and can be hazardous to health and the environment. Appropriate protective measures should be taken during operation, such as wearing protective glasses and gloves to ensure good ventilation. At the same time, it should avoid contact with fire sources and strong oxidants.

Last Update：2024-04-09 21:11:58