(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
FMoc-Val-Cit-PAB
CAS: 159858-22-7
Molecular Formula: C33H39N5O6
(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate - Names and Identifiers
(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate - Physico-chemical Properties
| Molecular Formula | C33H39N5O6 |
| Molar Mass | 601.69 |
| Density | 1.276±0.06 g/cm3(Predicted) |
| Melting Point | 204 °C(dec.) |
| Boling Point | 914.2±65.0 °C(Predicted) |
| Solubility | DMSO: ≥ 123.75 mg/mL |
| pKa | 10.63±0.46(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Physical and Chemical Properties | Bioactive Fmoc-Val-Cit-PAB (Fmoc-Val-Cit-PAB-OH) is a cleavable antibody-coupled drug (ADC) connection bridge |
| Use | Uses Fmoc-Val-Cit-PAB used in laboratory research and development process and chemical medicine synthesis process. |
(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate - Upstream Downstream Industry
(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.662 ml | 8.31 ml | 16.62 ml |
| 5 mM | 0.332 ml | 1.662 ml | 3.324 ml |
| 10 mM | 0.166 ml | 0.831 ml | 1.662 ml |
| 5 mM | 0.033 ml | 0.166 ml | 0.332 ml |
Last Update：2024-01-02 23:10:35
(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate - Introduction
Fmoc-Val-Cit-PAB is a degradable (cleavable) antibody-coupled drug (ADC) commonly used) connection bridge.
Last Update：2024-04-10 22:29:15
(9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate - Reference Information
| introduction | Fmoc-Val-Cit-PAB is a degradable (cleavable) antibody-coupled drug (ADC) commonly used) connection bridge. Fmoc-Val-Cit-PAB is a commonly used connection bridge for degradable antibody-coupled drugs (ADC). |
| use | Fmoc-Val-Cit-PAB used in laboratory research and development process and chemical medicine synthesis process. |
| biological activity | Fmoc-Val-Cit-PAB (Fmoc-Val-Cit-PAB-OH) is a cleavable antibody-coupled drug (ADC) connection bridge |
| target | Cleavable |
Last Update：2024-04-09 01:59:59
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Product Name: Fmoc-Val-Cit-PAB Visit Supplier Webpage Request for quotationCAS: 159858-22-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for (9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
Carbamic acid, N-[(1S)-4-[(aminocarbonyl)amino]-1-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]butyl]-, 1,1-dimethylethyl ester
N5-(aminocarbonyl)-N2-[(phenylmethoxy)carbonyl]-L-ornithine
4-Aminobenzyl alcohol
H-Cit-PABA
Fmoc-Cit-PABA
9-Fluorenylmethyl chloroformate
N5-(aminocarbonyl)-N2-[(phenylmethoxy)carbonyl]-L-ornithine
4-Aminobenzyl alcohol
H-Cit-PABA
Fmoc-Cit-PABA
9-Fluorenylmethyl chloroformate
Downstream Products for (9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
MC-Val-Cit-PAB
FMoc-Val-Cit-PAB-PNP
L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-
FMoc-Val-Cit-PAB-PNP
L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-