(R)-(+)-2-(Boc-Amino)-1,4-Butanediol

(R)-(+)-2-(Boc-Amino)-1,4-Butanediol - Names and Identifiers

Name	(R)-(+)-2-(Boc-Amino)-1,4-butanediol
Synonyms	(R)-2-Boc-amino-butane-1,4-diol (R)-(+)-2-(Boc-Amino)-1,4-butanediol (R)-(+)-2-(Boc-Amino)-1,4-Butanediol -tert-Butyl (1,4-dihydroxybutan-2-yl) (2R)-(tert-Butoxycarbonylamino)butane-1,4-diol (R)-TERT-BUTYL 1,4-DIHYDROXYBUTAN-2-YLCARBAMATE tert-butyl [(2R)-1,4-dihydroxybutan-2-yl]carbamate N-(1,4-dihydroxybutan-2-yl)carbamic acid tert-butyl ester [(1R)-3-Hydroxy-1-(hydroxymethyl)propyl]carbamic acid tert-butyl ester [(1R)-3-Hydroxy-1-(hydroxymethyl)propyl]carbamic acid tert-butyl ester Carbamic acid, [(1R)-3-hydroxy-1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl
CAS	397246-14-9
EINECS	210-006-7
InChI	InChI=1/C9H19NO4/c1-9(2,3)14-8(13)10-7(6-12)4-5-11/h7,11-12H,4-6H2,1-3H3,(H,10,13)/t7-/m1/s1

(R)-(+)-2-(Boc-Amino)-1,4-Butanediol - Physico-chemical Properties

Molecular Formula	C9H19NO4
Molar Mass	205.25
Density	1.110
Melting Point	64-68 °C
Boling Point	365.0±32.0 °C(Predicted)
Flash Point	174.571°C
Vapor Presure	0mmHg at 25°C
Appearance	Crystalline Powder
Color	White
pKa	11.81±0.46(Predicted)
Storage Condition	2-8°C
Refractive Index	1.476
MDL	MFCD08703679

(R)-(+)-2-(Boc-Amino)-1,4-Butanediol - Introduction

(R)-( )-2-(Boc-Amino)-1,4-butanediol, also known as (R)-( )-2-(Boc-Amino)-1,4-butanediol, is an organic compound, commonly known by the abbreviation (R)-( )-Boc-Amino-Butanediol. It has a molecular formula of C10H21NO4 and a molecular weight of 219.28g/mol.

Nature:
(R)-( )-2-(Boc-Amino)-1,4-butanediol is a solid with a white to almost white color. It has the property of being soluble in polar solvents, such as alcohols and esters, and insoluble in non-polar solvents. The compound has optical activity, optical rotation, optical rotation is [α]25D = 16 °. It is a chiral molecule with two stereocenters.

Use:
(R)-( )-2-(Boc-Amino)-1,4-butanediol is widely used as a reagent or intermediate in organic synthesis. Its main applications include drug synthesis, ligand synthesis, and chiral control in organic synthesis. As a chiral building block, it can be used in the synthesis of chiral drugs, ligands and chiral polymer materials.

Preparation Method:
(R)-( )-2-(Boc-Amino)-1,4-butanediol is usually prepared by reacting (R)-( )-2-amino -1,4-butanediol with N-tert-butoxycarbonylimine. This reaction is generally carried out under neutral or basic conditions, and the product obtained after the reaction can be purified by crystallization.

Safety Information:
The best way to confirm the safe use and handling of compounds is to consult the relevant chemical literature and follow proper laboratory procedures. In general, handle and store compounds properly, avoiding contact with eyes, skin, and inhalation. If contact occurs, rinse immediately with plenty of water. Also, work in a well-ventilated environment and wear appropriate protective equipment, including laboratory gloves and goggles.

Last Update：2024-04-09 21:32:40