(R)-1-Benzyloxycarbonyl-3-pyrrolidinol, (R)-1-Carbobenzoxy-3-pyrrolidinol, (R)-N-Z-3-Pyrrolidinol
(R)-1-Cbz-3-Pyrrolidinol
CAS: 100858-33-1
Molecular Formula: C12H15NO3
(R)-1-Benzyloxycarbonyl-3-pyrrolidinol, (R)-1-Carbobenzoxy-3-pyrrolidinol, (R)-N-Z-3-Pyrrolidinol - Names and Identifiers
(R)-1-Benzyloxycarbonyl-3-pyrrolidinol, (R)-1-Carbobenzoxy-3-pyrrolidinol, (R)-N-Z-3-Pyrrolidinol - Physico-chemical Properties
| Molecular Formula | C12H15NO3 |
| Molar Mass | 221.25 |
| Density | 1.263±0.06 g/cm3(Predicted) |
| Melting Point | 74-79°C |
| Boling Point | 370.7±42.0 °C(Predicted) |
| Flash Point | 178°C |
| Vapor Presure | 3.75E-06mmHg at 25°C |
| pKa | 14.72±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.589 |
| Physical and Chemical Properties | WGK Germany:3 |
(R)-1-Benzyloxycarbonyl-3-pyrrolidinol, (R)-1-Carbobenzoxy-3-pyrrolidinol, (R)-N-Z-3-Pyrrolidinol - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
(R)-1-Benzyloxycarbonyl-3-pyrrolidinol, (R)-1-Carbobenzoxy-3-pyrrolidinol, (R)-N-Z-3-Pyrrolidinol - Introduction
N-CBZ-3-(R)-Hydroxypyrrolidine, also known as N-CBZ-(R)-3-Hydroxypyrrolidine, is an organic compound. It is a white crystalline solid with some solubility. The compound has chirality, and because of the different substituents, it can have different stereoisomers.
N-CBZ-3-(R)-hydroxypyrrolidine is widely used in chemical synthesis. It can be used as an intermediate for the synthesis of drugs, hybrid materials and bioactive molecules. It can be used in the synthesis of amino acids, peptides and other nitrogen-containing organic compounds. It is also widely used in sugar chemistry and natural product synthesis.
A common method for preparing N-CBZ-3-(R)-hydroxypyrrolidine is to reduce N-CBZ-3-(R)-hydroxypyrrolidine by a catalytic hydrogenation reduction reaction. Reaction conditions generally require selection of appropriate catalyst, temperature, and pressure to achieve high yields.
For safety information, N-CBZ-3-(R)-Hydroxypyrrolidine is less toxic and hazardous. However, appropriate chemical laboratory safety measures should still be taken when handling the compound, such as wearing laboratory gloves, goggles and protective clothing, and avoiding inhalation, contact with skin and eyes. At the same time, ensure operation in a well-ventilated environment. During storage, the compound should be kept in a dry, cool place, away from flammable, explosive substances and oxidizing agents.
N-CBZ-3-(R)-hydroxypyrrolidine is widely used in chemical synthesis. It can be used as an intermediate for the synthesis of drugs, hybrid materials and bioactive molecules. It can be used in the synthesis of amino acids, peptides and other nitrogen-containing organic compounds. It is also widely used in sugar chemistry and natural product synthesis.
A common method for preparing N-CBZ-3-(R)-hydroxypyrrolidine is to reduce N-CBZ-3-(R)-hydroxypyrrolidine by a catalytic hydrogenation reduction reaction. Reaction conditions generally require selection of appropriate catalyst, temperature, and pressure to achieve high yields.
For safety information, N-CBZ-3-(R)-Hydroxypyrrolidine is less toxic and hazardous. However, appropriate chemical laboratory safety measures should still be taken when handling the compound, such as wearing laboratory gloves, goggles and protective clothing, and avoiding inhalation, contact with skin and eyes. At the same time, ensure operation in a well-ventilated environment. During storage, the compound should be kept in a dry, cool place, away from flammable, explosive substances and oxidizing agents.
Last Update：2024-04-09 21:11:58
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CAS: 100858-33-1
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CAS: 100858-33-1
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View History
(R)-1-Benzyloxycarbonyl-3-pyrrolidinol, (R)-1-Carbobenzoxy-3-pyrrolidinol, (R)-N-Z-3-Pyrrolidinol
莱鲍迪苷
4-chloro-N,N-dimethylbenzamide
莱鲍迪苷
4-chloro-N,N-dimethylbenzamide