(R)-2-((叔丁氧基羰基)(甲基)氨基)-3-甲基丁酸 - Names and Identifiers
(R)-2-((叔丁氧基羰基)(甲基)氨基)-3-甲基丁酸 - Physico-chemical Properties
Molecular Formula | C11H21NO4
|
Molar Mass | 231.29 |
Density | 1.069 |
Boling Point | 322℃ |
Flash Point | 140℃ |
Appearance | Solid |
pKa | 4.03±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
(R)-2-((叔丁氧基羰基)(甲基)氨基)-3-甲基丁酸 - Risk and Safety
(R)-2-((叔丁氧基羰基)(甲基)氨基)-3-甲基丁酸 - Introduction
Boc-N-Me-D-Val-OH(Boc-N-Me-D-Val-OH) is an organic compound with the following properties:
Nature:
1. Chemical formula: C16H31NO5
2. molecular weight: 329.42g/mol
3. Appearance: white crystal powder
4. melting point: 85-87 degrees Celsius
5. Solubility: Soluble in organic solvents (such as methanol, ether), slightly soluble in water.
Use:
Boc-N-Me-D-Val-OH are commonly used in peptide synthesis and drug research in organic synthesis. It can be used as a protecting group or as an intermediate in the synthesis of polypeptides and other complex organic compounds.
Preparation Method:
A common preparation method is to react N-tert-butoxycarbonyl-D-valine with methylmagnesium bromide to obtain Boc-N-Me-D-Val-OH. The specific steps are as follows:
1. Add N-t-butoxycarbonyl-D-valine to solvent-free ether.
2. Methyl magnesium bromide was slowly added dropwise to the reaction solution.
3. Control the temperature during the reaction and stir well.
4. After the reaction is completed, a saturated ammonium chloride solution is added to react the magnesium ions in the reaction solution with chloride ions to generate a precipitate.
5. The precipitate was filtered and washed with ether to give the product Boc-N-Me-D-Val-OH.
Safety Information:
Boc-N-Me-D-Val-OH are not particularly dangerous compounds, but still need to be handled with caution. General attention to the following safety matters:
1. Avoid inhalation, ingestion or skin contact. Wear appropriate personal protective equipment such as lab gloves, goggles, and lab clothes during operation.
2. Operate in a well-ventilated place to avoid dust or steam. Avoid contact with harmful substances such as oxidants and strong acids/bases.
3. in strict accordance with the instructions and safety operation procedures for operation, to avoid accidents.
Tip: When conducting any chemical tests or using chemicals, be sure to follow safe operating procedures and consult a professional for guidance.
Last Update:2024-04-09 02:00:49