(R)-a-(Fmoc-amino)-4-hydroxybenzeneacetic acid

(R)-a-(Fmoc-amino)-4-hydroxybenzeneacetic acid - Names and Identifiers

Name	Fmoc-D-4-Hydroxyphenylglycine
Synonyms	Fmoc-DnTyr-OH Fmoc-D-4-Hydroxyphenylglycine Nα-Fmoc-(4-hydroxy)-D-phenylglycine (R)-a-(Fmoc-amino)-4-hydroxybenzeneacetic acid (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-(4-hydroxyphenyl)acetic acid (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-(4-hydroxyphenyl)acetic acid Benzeneacetic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-hydroxy-, (αR)-
CAS	178119-93-2
EINECS	1533716-785-6

(R)-a-(Fmoc-amino)-4-hydroxybenzeneacetic acid - Physico-chemical Properties

Molecular Formula	C23H19NO5
Molar Mass	389.4
Storage Condition	2-8°C

(R)-a-(Fmoc-amino)-4-hydroxybenzeneacetic acid - Introduction

Fmoc-D-4-Hydroxyphenylglycine(Fmoc-D-4-hydroxyphenylglycine) is an organic compound with the following properties:

1. Appearance: solid, often white or similar color.
2. Solubility: Soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane (DCM).
3. Storage conditions: Store in a dry, sealed container, avoid direct sunlight.

Fmoc-D-4-Hydroxyphenylglycine have the following main uses:

1. In pharmaceutical chemical synthesis, it can be used as one of the amino acid units in polypeptide synthesis. Its hydroxyl functionality can be used for reaction directing, for example by esterification to form an ester bond. It can also be used as a building block for drug molecules.
2. In the research field, it can be used for self-assembly research and construction of molecules with specific functions.

The method of preparing Fmoc-D-4-Hydroxyphenylglycine usually involves the following steps:

1. First, 4-hydroxyphenylglycine was synthesized from phenylglycine through a series of reactions.
2. Next, The Fmoc protecting group was introduced into 4-hydroxyphenylglycine to obtain Fmoc-D-4-Hydroxyphenylglycine.

When using or handling Fmoc-D-4-Hydroxyphenylglycine, you need to use caution and take appropriate safety measures:

1. Pay attention to personal protection, such as wearing appropriate protective gloves, glasses and laboratory coats.
2. Avoid inhalation or contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical advice.
3. During use, maintain a well-ventilated laboratory environment to avoid inhaling harmful gases or vapors.

Last Update：2024-04-09 21:01:54