(S)-(+)-1-PHENYLETHANEDIOL 2-TOSYLATE

(S)-(+)-1-PHENYLETHANEDIOL 2-TOSYLATE - Names and Identifiers

Name	(S)-(+)-1-phenyl-1,2-ethanediol 2-tosylate
Synonyms	(S)-(+)-1-PHENYLETHANEDIOL 2-TOSYLATE (S)-(+)-1-phenyl-1,2-ethanediol 2-tosylate (S)-(+)-1-PHENYL-1,2-ETHANEDIOL 2-TOSYLATE (S)-(+)-1-Phenyl-1,2-Ethanediol 2-Tosylate (S)-(+)-1-PHENYLETHANE-1,2-DIOL 2-TOSYLATE (S)-(+)-1-Phenylethane-1,2-diol 2-tosylate (S)-(+)-2-HYDROXY-2-PHENYLETHYL P-TOLUENESULFONATE (2S)-2-hydroxy-2-phenylethyl 4-methylbenzenesulfonate (S)-(+)-2-Hydroxy-2-phenylethyl 4-methylbenzenesulfonate 1,2-Ethanediol, 1-phenyl-, 2-(4-methylbenzenesulfonate), (1S)-
CAS	40435-14-1
InChI	InChI=1/C15H16O4S/c1-12-7-9-14(10-8-12)20(17,18)19-11-15(16)13-5-3-2-4-6-13/h2-10,15-16H,11H2,1H3/t15-/m1/s1

(S)-(+)-1-PHENYLETHANEDIOL 2-TOSYLATE - Physico-chemical Properties

Molecular Formula	C15H16O4S
Molar Mass	292.35
Density	1.274±0.06 g/cm3(Predicted)
Melting Point	74-76 °C (lit.)
Boling Point	480.6±40.0 °C(Predicted)
Specific Rotation(α)	34 º (C=2 IN ETOH)
Flash Point	244.5°C
Vapor Presure	4.77E-10mmHg at 25°C
Appearance	White powder
Color	White
pKa	12.95±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.59
MDL	MFCD00013428

(S)-(+)-1-PHENYLETHANEDIOL 2-TOSYLATE - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29062990

(S)-(+)-1-PHENYLETHANEDIOL 2-TOSYLATE - Introduction

(S)-(+)-1-phenyl-1,2-ethanediol 2-tosylate is an organic compound containing a phenyl group and an ethylene glycol group in its chemical structure. Its molecular formula is C16H18O5S and its relative molecular mass is 338.38g/mol. This compound is a chiral molecule with optical rotation and positive optical rotation. It is a solid, common form is white crystals.

(S)-( )-1-phenyl-1,2-ethanediol 2-tosylate has important applications in organic synthesis. It can be used as a chiral inducer for the synthesis of other organic compounds with chirality. This compound can also be used as a chiral catalyst for catalytic asymmetric synthesis reactions. Due to its chiral properties, it also has certain applications in biology and medicinal chemistry research.

The method of preparing (S)-( )-1-phenyl-1,2-ethanediol 2-tosylate generally involves three steps. First, benzyl alcohol is oxidized by an oxidation reaction to produce benzaldehyde. Benzaldehyde is then reacted with subethanolic acid to yield (S)-(+)-1-phenyl-1,2-ethanediol 2-tosylate. Finally, esterification with toluenesulfonic acid was carried out to give the final product.

Regarding safety information, (S)-( )-1-phenyl-1,2-ethanediol 2-tosylate is a chemical that needs to be properly handled in laboratories or industrial production. When using, you need to pay attention to prevent contact with the skin and eyes, and avoid inhaling its particles or smoke. You should operate in a well-ventilated area and wear appropriate protective equipment such as gloves, safety glasses and protective clothing. If exposed or inhaled, rinse immediately with clean water and seek medical help.

Last Update：2024-04-09 21:01:54