(S)-(-)-4-CHLORO A-METHYLBENZYLAMINE
(S)-1-(4-Chlorophenyl)ethylamine
CAS: 4187-56-8
Molecular Formula: C8H10ClN
(S)-(-)-4-CHLORO A-METHYLBENZYLAMINE - Names and Identifiers
| Name | (S)-1-(4-Chlorophenyl)ethylamine |
| Synonyms | (S)-4-Chloro-α-methylbenzylamine (S)-1-(4-CHLOROPHENYL)ETHANAMINE (S)-1-(4-CHLOROPHENYL)ETHYLAMINE (S)-1-(4-Chlorophenyl)ethylamine (1S)-1-(4-chlorophenyl)ethanamine (S)-(-)-1-(4-CHLOROPHENYL)ETHYLAMINE (S)-4-Chloro-alpha-methylbenzylamine (S)-4-CHLORO-ALPHA-METHYLBENZYLAMINE (S)-(-)-1-(4-Chlorophenyl)ethylamine (S)-(-)-4-CHLORO A-METHYLBENZYLAMINE (S)-4-Chloro-alpha-methylbenzylamine~ClophaS(tm |
| CAS | 4187-56-8 |
| EINECS | 609-965-8 |
| InChI | InChI=1/C8H10ClN/c1-6(10)7-2-4-8(9)5-3-7/h2-6H,10H2,1H3/t6-/m0/s1 |
(S)-(-)-4-CHLORO A-METHYLBENZYLAMINE - Physico-chemical Properties
| Molecular Formula | C8H10ClN |
| Molar Mass | 155.63 |
| Density | 1.110g/mLat 20°C(lit.) |
| Melting Point | 136-137 °C |
| Boling Point | 232 °C |
| Specific Rotation(α) | -23.5 º (C=2, MEOH) |
| Flash Point | 232°C |
| Water Solubility | VERY LOW SOLUBILITY |
| Vapor Presure | 0.0842mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear pale yellow |
| BRN | 2412316 |
| pKa | 8.82±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.543(lit.) |
(S)-(-)-4-CHLORO A-METHYLBENZYLAMINE - Risk and Safety
| Risk Codes | R25 - Toxic if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R34 - Causes burns R22 - Harmful if swallowed R43 - May cause sensitization by skin contact R38 - Irritating to the skin R37 - Irritating to the respiratory system R23 - Toxic by inhalation |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 2 |
| FLUKA BRAND F CODES | 10-34 |
| HS Code | 29211990 |
| Hazard Class | 8 |
| Packing Group | II |
(S)-(-)-4-CHLORO A-METHYLBENZYLAMINE - Introduction
(S)-1-(4-Chlorophenyl)ethylamine is an organic compound with the chemical formula C8H10ClN. It is a chiral molecule with optical properties and is called (S)-trans-ethylamine in optical activity. The compound is a colorless to pale yellow liquid with a persistent sour taste.
(S)-1-(4-Chlorophenyl)ethylamine is generally used as a pharmaceutical intermediate for the synthesis of various drugs. It can be used in the synthesis of antidepressants, antipsychotics and precursors of drugs such as proindacillin.
Methods for preparing (S)-1-(4-Chlorophenyl)ethylamine generally involve chiral synthesis techniques. A common method is by condensation of 4-chloroacetophenone with optically pure isopropylamine to give the desired chiral product.
When handling and using (S)-1-(4-Chlorophenyl)ethylamine, certain safety measures need to be taken. It is an organic solvent that is irritating and should be avoided by inhalation or contact with skin and eyes. Wear appropriate protective equipment such as gloves, goggles and protective clothing during use. In addition, the compound needs to be stored and handled properly to prevent leakage and accidents. For specific safety information and operating instructions, reference should be made to the safety data sheet of the compound and the safety operating instructions for the relevant chemical.
(S)-1-(4-Chlorophenyl)ethylamine is generally used as a pharmaceutical intermediate for the synthesis of various drugs. It can be used in the synthesis of antidepressants, antipsychotics and precursors of drugs such as proindacillin.
Methods for preparing (S)-1-(4-Chlorophenyl)ethylamine generally involve chiral synthesis techniques. A common method is by condensation of 4-chloroacetophenone with optically pure isopropylamine to give the desired chiral product.
When handling and using (S)-1-(4-Chlorophenyl)ethylamine, certain safety measures need to be taken. It is an organic solvent that is irritating and should be avoided by inhalation or contact with skin and eyes. Wear appropriate protective equipment such as gloves, goggles and protective clothing during use. In addition, the compound needs to be stored and handled properly to prevent leakage and accidents. For specific safety information and operating instructions, reference should be made to the safety data sheet of the compound and the safety operating instructions for the relevant chemical.
Last Update：2024-04-09 20:52:54
