(S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol
(S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol
CAS: 80655-81-8
Molecular Formula: C20H12Br2O2
(S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol - Names and Identifiers
| Name | (S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol |
| Synonyms | AURORA KA-7214 6'-DIBROMO-1,1'-BI-2-NAPHTHOL 6,6'-DIBROMO-1,1'-BI-2-NAPHTHOL (R)-(-)-6,6'-DIBROMO-1,1'-BI-NAPHTHOL (S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol (R)-(-)-6,6'-DIBROMO 1,1'-BL-2-NAPHTHOL (R)-(-)-6,6'-DIBROMO-2,2'-DIHYDROXY-1,1'-BINAPHTHYL |
| CAS | 80655-81-8 |
| EINECS | 632-860-3 |
(S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol - Physico-chemical Properties
| Molecular Formula | C20H12Br2O2 |
| Molar Mass | 444.12 |
| Density | 1.5428 (rough estimate) |
| Melting Point | 195-199°C(lit.) |
| Boling Point | 546.2±45.0 °C(Predicted) |
| pKa | 7.78±0.50(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.4947 (estimate) |
(S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29081990 |
(S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol - Introduction
(S)-(-)-6,6 '-Dibromo-1,1'-bi-2-naphthol is a chiral molecule with the formula C20H12Br2O. It is a white or white yellow crystalline solid, can be dissolved in chloroform, dichloromethane, ethanol and other organic solvents.
This compound has important applications in synthetic organic chemistry. It can be used as a chiral inducer to catalyze asymmetric synthesis reactions. It can participate in the direct reaction of asymmetric amino alcohol catalyzed aldol and generate chiral amines. In addition, it can also be used as a synthetic intermediate for the synthesis of chiral drugs and heterocyclic compounds.
(S)-(-)-6,6 '-Dibromo-1,1'-bi-2-naphthol is generally prepared by reacting 2-naphthol with bromine in the presence of sodium carbonate or cesium carbonate. After completion of the reaction, the target product was obtained by crystallization and separation purification.
For safety information, this compound should be stored in a dry, well-ventilated place, away from fire and oxidizing agents. Wear appropriate protective equipment such as goggles and gloves during operation. The effects on the human body are not yet understood in detail, so care should be taken. Seek medical help if exposed or ingested.
This compound has important applications in synthetic organic chemistry. It can be used as a chiral inducer to catalyze asymmetric synthesis reactions. It can participate in the direct reaction of asymmetric amino alcohol catalyzed aldol and generate chiral amines. In addition, it can also be used as a synthetic intermediate for the synthesis of chiral drugs and heterocyclic compounds.
(S)-(-)-6,6 '-Dibromo-1,1'-bi-2-naphthol is generally prepared by reacting 2-naphthol with bromine in the presence of sodium carbonate or cesium carbonate. After completion of the reaction, the target product was obtained by crystallization and separation purification.
For safety information, this compound should be stored in a dry, well-ventilated place, away from fire and oxidizing agents. Wear appropriate protective equipment such as goggles and gloves during operation. The effects on the human body are not yet understood in detail, so care should be taken. Seek medical help if exposed or ingested.
Last Update：2024-04-09 20:49:11
