(S)-1-(4-NITROPHENYL)-METHYLAMIN HYDROCHLORIDE
(S)-(-)-A-methyl 4-nitrobenzylamine hydrochloride
CAS: 132873-57-5
Molecular Formula: C8H11ClN2O2
(S)-1-(4-NITROPHENYL)-METHYLAMIN HYDROCHLORIDE - Names and Identifiers
(S)-1-(4-NITROPHENYL)-METHYLAMIN HYDROCHLORIDE - Physico-chemical Properties
| Molecular Formula | C8H11ClN2O2 |
| Molar Mass | 202.64 |
| Melting Point | 248-250°C(lit.) |
| Boling Point | 321.3°C at 760 mmHg |
| Flash Point | 148.1°C |
| Water Solubility | faint turbidity |
| Vapor Presure | 0.000219mmHg at 25°C |
| Appearance | White to yellow to brown powder |
| Color | White to Light yellow |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | -7.2 ° (C=1, 0.05mol |
| MDL | MFCD00066312 |
(S)-1-(4-NITROPHENYL)-METHYLAMIN HYDROCHLORIDE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29214990 |
(S)-1-(4-NITROPHENYL)-METHYLAMIN HYDROCHLORIDE - Introduction
(S)-α-methyl-4-nitrobenzylamine hydrochloride is an organic compound with the chemical formula C8H9N3O3 · HCl. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline powder
-Melting point: 197-200°C
-Solubility: Soluble in water and alcohol solvents, slightly soluble in ether solvents
-Optically active: Chiral, an optically active compound
Use:
- (S)-α-methyl-4-nitrobenzylamine hydrochloride is an important intermediate compound, which is widely used in pharmaceutical manufacturing, especially in the synthesis of chiral drugs.
-It can be used as a raw material for chiral catalysts to prepare high-purity selective drugs and compounds.
Preparation Method:
The preparation of (S)-α-methyl-4-nitrobenzylamine hydrochloride can be carried out by the following steps:
1. Benzaldehyde reacts with nitric acid under alkaline conditions to generate α-nitrobenzyl alcohol.
2. reacting α-nitrobenzyl alcohol with methylamine to generate α-methyl -4-nitrobenzyl amine.
3. reacting α-methyl-4-nitrobenzylamine with hydrochloric acid to generate (S)-α-methyl-4-nitrobenzylamine hydrochloride.
Safety Information:
- (S)-α-methyl-4-nitrobenzylamine hydrochloride is a chemical and should be handled in strict accordance with safe operating procedures.
-It may be irritating to the skin, eyes and respiratory system.
-Wear appropriate protective equipment such as protective gloves, safety glasses and respiratory protection during use.
-Avoid inhaling dust, contact with skin and eyes.
-In case of contact or ingestion, rinse immediately with plenty of water and seek medical help.
Nature:
-Appearance: White crystalline powder
-Melting point: 197-200°C
-Solubility: Soluble in water and alcohol solvents, slightly soluble in ether solvents
-Optically active: Chiral, an optically active compound
Use:
- (S)-α-methyl-4-nitrobenzylamine hydrochloride is an important intermediate compound, which is widely used in pharmaceutical manufacturing, especially in the synthesis of chiral drugs.
-It can be used as a raw material for chiral catalysts to prepare high-purity selective drugs and compounds.
Preparation Method:
The preparation of (S)-α-methyl-4-nitrobenzylamine hydrochloride can be carried out by the following steps:
1. Benzaldehyde reacts with nitric acid under alkaline conditions to generate α-nitrobenzyl alcohol.
2. reacting α-nitrobenzyl alcohol with methylamine to generate α-methyl -4-nitrobenzyl amine.
3. reacting α-methyl-4-nitrobenzylamine with hydrochloric acid to generate (S)-α-methyl-4-nitrobenzylamine hydrochloride.
Safety Information:
- (S)-α-methyl-4-nitrobenzylamine hydrochloride is a chemical and should be handled in strict accordance with safe operating procedures.
-It may be irritating to the skin, eyes and respiratory system.
-Wear appropriate protective equipment such as protective gloves, safety glasses and respiratory protection during use.
-Avoid inhaling dust, contact with skin and eyes.
-In case of contact or ingestion, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:51
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Product Name: (S)-(-)-A-methyl 4-nitrobenzylamine hydrochloride Request for quotation
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CAS: 132873-57-5
Tel: 17505222756
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Product Name: (S)-Alpha-Methyl-4-Nitrobenzylamine Hydrochloride Visit Supplier Webpage Request for quotationCAS: 132873-57-5
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