Name | L-lysine acetate |
Synonyms | L-LYS AC L-LYSINE AC L-lysine Hac H-LYS-OH ACOH L-lysine acetate L-LYSINE ACETATE USP L-Lysine monoacetate L-LYSINE ACETATE SALT L-Lysine acetate salt L-LYSINE ACETATE USP STANDARD (s)-2,6-diaminohexanoic acid acetate salt (S)-2,6-Diaminohexanoic acid acetate salt acetic acid, (2R)-2,6-diaminohexanoic acid |
CAS | 57282-49-2 52315-76-1 |
EINECS | 260-664-4 |
InChI | InChI=1/C6H14N2O2.C2H4O2/c7-4-2-1-3-5(8)6(9)10;1-2(3)4/h5H,1-4,7-8H2,(H,9,10);1H3,(H,3,4)/t5-;/m1./s1 |
Molecular Formula | C8H18N2O4 |
Molar Mass | 206.24 |
Boling Point | 441°C at 760 mmHg |
Flash Point | 220.5°C |
Solubility | Freely soluble in water, very slightly soluble in ethanol (96 per cent). |
Vapor Presure | 5.22E-09mmHg at 25°C |
Appearance | Crystallization |
Storage Condition | 2-8°C |
Use | Used as amino acid drugs |
WGK Germany | 2 |
RTECS | OL5644200 |
HS Code | 29224110 |
white crystals or crystalline powders. The melting point was 191-193 °c. When the relative humidity exceeds 60%, this product has strong hygroscopicity. This product is lysine acetate, used to replace lysine hydrochloride for intravenous infusion of crystalline amino acid injection can prevent concurrent hyperchloremia Metabolic Acidosis.
amino acid drugs. Instead of lysine hydrochloride to prevent lysine hydrochloride complicated by Hyperchloremia Metabolic Acidosis.
mouse oral, LD50 13. 4~14. 4g/kg; The oral LD50 of rats was 11.4~14. 5g/kg; Intraperitoneal injection, LD50 3.7~3. 95g/kg, intravenous injection, LD50 2. 85~3. 65 g/kg.
Overview | lysine acetate, molecular formula C6H14N2O2, is a white crystal or crystalline powder; Almost odorless; Soluble in water. Lysine acetate is one of the essential amino acids in human body. It not only participates in some metabolic processes, but also affects the metabolism and absorption of other amino acids. Existing research results show that: lysine can inhibit the simple scar rash Virus of the replication, the treatment of angina, myocardial infarction has a preventive effect, improve the memory function of patients with memory loss, it itself also has a barbiturate-like anticonvulsant effect. In medicine can be used for the preparation of amino acid injection and oral preparation. For the preparation of amino acid injection and oral preparations; Diuretic auxiliary drugs, the treatment of lead poisoning caused by the reduction of chloride in the blood; Can produce salts with acidic drugs to reduce adverse reactions. |
Application | lysine is one of the main raw materials for compound amino acid injection. Due to the poor chemical stability of lysine, it is often made into lysine hydrochloride for application in the early stage. The compound amino acid infusion prepared with lysine hydrochloride has high chloride ion content, and some patients are not suitable. Therefore, lysine acetate is currently used to prepare amino acid infusions. Examples of its application are as follows: 1. For the preparation of 18 kinds of amino acid glucose. 18 kinds of amino acid glucose is clear liquid, containing L-leucine, L-proline, L-isoleucine, L-phenylalanine, L-lysine acetate, L-threonine, L-methionine, L-tryptophan, L-histidine (N-acetyl-L-tryptophan), L-tyrosine, L-valine, L-alanine, L-serine, glycine, L-arginine, L-aspartic acid, L-cysteine hydrochloride, L-glutamic acid, glucose. It can provide energy for protein synthesis, inhibit amino acid heterogenic glycogen, and promote the full use of amino acids. This product is more convenient and reasonable than single amino acid infusion. It is suitable for improving the nutritional status of patients before and after surgery, treating malnutrition caused by various diseases, and can be used as nitrogen saving therapy to supplement nutrition. 2. Used for preparation Compound Amino Acid Injection(14AA). Compound Amino Acid Injection(14AA) (3%) containing isoleucine 2.1g, leucine 2.7g, lysine acetate 3.1g, methionine 1.6g, phenylalanine 1.7g, threonine 1.2g, tryptophan 0.46g, valine 2.0g, alanine 2.1g, arginine 2.9g, histidine 0.85g, proline 3.4g, serine 4.2g, glycine 0.5g, sodium bisulfite 30.0g, glycerol g. |
Use | use as amino acid drug |
EPA chemical substance information | information is provided by: ofmpeb.epa.gov (external link) |