(S)-2-(6-Hydroxy-2-naphthyl)propionic Acid
(S)-O-Desmethyl Naproxen
CAS: 52079-10-4
Molecular Formula: C13H12O3
(S)-2-(6-Hydroxy-2-naphthyl)propionic Acid - Names and Identifiers
(S)-2-(6-Hydroxy-2-naphthyl)propionic Acid - Physico-chemical Properties
| Molecular Formula | C13H12O3 |
| Molar Mass | 216.23 |
| Density | 1.297±0.06 g/cm3(Predicted) |
| Melting Point | 182-183°C |
| Boling Point | 432.1±20.0 °C(Predicted) |
| Appearance | neat |
| Color | white |
| BRN | 8838512 |
| pKa | 4.87±0.30(Predicted) |
| Storage Condition | 2-8°C |
(S)-2-(6-Hydroxy-2-naphthyl)propionic Acid - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R43 - May cause sensitization by skin contact R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S36/37 - Wear suitable protective clothing and gloves. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9/PG 3 |
| WGK Germany | 3 |
(S)-2-(6-Hydroxy-2-naphthyl)propionic Acid - Introduction
(S)-O-Desmethyl Naproxen ((S)-O-Desmethyl Naproxen) is a compound, which is a desmethyl compound of the levorotatory body, commonly abbreviated as (S)-DMN. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
(S)-O-Desmethyl Naproxen is a white crystalline solid whose structure is similar to the methoxy compound Naproxen (Naproxen), except that the methyl group is removed. It has pharmaceutical activity and can be used as an intermediate of non-steroidal anti-inflammatory drugs.
Use:
(S)-O-Desmethyl Naproxen is an important pharmaceutical intermediate. It can be used to synthesize non-steroidal drugs with anti-inflammatory and analgesic effects. Naproxen is a drug that reduces prostaglandin synthesis in the body by inhibiting epoxidase activity, and (S)-O-Desmethyl is an important intermediate for the synthesis of Naproxen.
Preparation Method:
(S)-O-Desmethyl Naproxen can be obtained by a demethylation reaction during the synthesis of Naproxen. The specific preparation method can be used as raw material, and (S)-DMN can be obtained by several steps of reaction.
Safety Information:
The safety of (S)-O-Desmethyl Naproxen has not been reported in particular detail. However, since it is a pharmaceutical intermediate, it should be handled in accordance with relevant laboratory and chemical safety practices. In General, exposure of the mouth or skin should be avoided and kept away from sources of ignition. If you come into contact with this compound, rinse immediately with plenty of water and seek medical assistance.
It should be noted that the information provided above is for reference only. If you use this compound, please be sure to follow the relevant laboratory safety practices, carefully read and follow the safety instructions provided with the chemical before use.
Nature:
(S)-O-Desmethyl Naproxen is a white crystalline solid whose structure is similar to the methoxy compound Naproxen (Naproxen), except that the methyl group is removed. It has pharmaceutical activity and can be used as an intermediate of non-steroidal anti-inflammatory drugs.
Use:
(S)-O-Desmethyl Naproxen is an important pharmaceutical intermediate. It can be used to synthesize non-steroidal drugs with anti-inflammatory and analgesic effects. Naproxen is a drug that reduces prostaglandin synthesis in the body by inhibiting epoxidase activity, and (S)-O-Desmethyl is an important intermediate for the synthesis of Naproxen.
Preparation Method:
(S)-O-Desmethyl Naproxen can be obtained by a demethylation reaction during the synthesis of Naproxen. The specific preparation method can be used as raw material, and (S)-DMN can be obtained by several steps of reaction.
Safety Information:
The safety of (S)-O-Desmethyl Naproxen has not been reported in particular detail. However, since it is a pharmaceutical intermediate, it should be handled in accordance with relevant laboratory and chemical safety practices. In General, exposure of the mouth or skin should be avoided and kept away from sources of ignition. If you come into contact with this compound, rinse immediately with plenty of water and seek medical assistance.
It should be noted that the information provided above is for reference only. If you use this compound, please be sure to follow the relevant laboratory safety practices, carefully read and follow the safety instructions provided with the chemical before use.
Last Update：2024-04-09 21:54:55
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View History
(S)-2-(6-Hydroxy-2-naphthyl)propionic Acid
双酚A二缩水甘油醚(E42型)
(+)-P-MENTH-1-ENE, TERPENE STANDARD
2-三氟甲基烟酸甲酯
Disulfide, bis(2-methylphenyl)
ETHYL, 2-ISOBUTYL ACETOACETATE
2-((2-(((5-(3-CHLOROPHENYL)-2-FURYL)METHYL)AMINO)ETHYL)AMINO)ETHANOL
1-溴苯并环丁烯
槲皮素 3-O-β-D-葡萄糖醛酸苷
三丁氧基硅醇
双酚A二缩水甘油醚(E42型)
(+)-P-MENTH-1-ENE, TERPENE STANDARD
2-三氟甲基烟酸甲酯
Disulfide, bis(2-methylphenyl)
ETHYL, 2-ISOBUTYL ACETOACETATE
2-((2-(((5-(3-CHLOROPHENYL)-2-FURYL)METHYL)AMINO)ETHYL)AMINO)ETHANOL
1-溴苯并环丁烯
槲皮素 3-O-β-D-葡萄糖醛酸苷
三丁氧基硅醇