(S)-3-AMinopiperidin-2-one HCl

(S)-3-AMinopiperidin-2-one HCl - Names and Identifiers

Name	(3S)-3-aminopiperidin-2-one
Synonyms	(S)-3-Amino-2-piperidinon (S)-3-AMino-2-piperidinone (S)-3-aminopiperidin-2-one (S)-3-AMINOPIPERIDINE-2-ONE (3S)-3-aminopiperidin-2-one (3S)-3-Aminopiperidin-2-one (S)-3-Aminopiperidine-2-one (3S)-3-aMinopiperidin-2-one (S)-(-)-3-Amino-2-piperidinon (S)-3-AMinopiperidin-2-one HCl (S)-3-AMinopiperidine-2-one HCl 2-Piperidinone, 3-amino-, (3S)- (3S)-3-aMinopiperidin-2-one hydrochloride (S)-3-AMino-piperidine-2-one hydrochloride
CAS	34294-79-6
InChI	InChI=1/C5H10N2O/c6-4-2-1-3-7-5(4)8/h4H,1-3,6H2,(H,7,8)/t4-/m0/s1

(S)-3-AMinopiperidin-2-one HCl - Physico-chemical Properties

Molecular Formula	C5H10N2O
Molar Mass	114.15
Density	1.071±0.06 g/cm3(Predicted)
Melting Point	87°C(lit.)
Boling Point	307.5±35.0 °C(Predicted)
Flash Point	139.8°C
Solubility	Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0.000723mmHg at 25°C
Appearance	Solid
Color	Light Yellow to Yellow
pKa	16.00±0.40(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.476
MDL	MFCD09259964

(S)-3-AMinopiperidin-2-one HCl - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HS Code	29333990

(S)-3-AMinopiperidin-2-one HCl - Introduction

(3S)-3-aminopiperidin-2-one is an organic compound with the chemical formula C6H12N2O. It is a white crystalline solid, soluble in water and some organic solvents.

(3S)-3-aminopiperidin-2-one has certain applications in the field of medicine. It is one of the synthetic intermediates of heparin, which can be obtained by the reaction of amino alcohol and cyclic ester. Heparin is a commonly used anticoagulant to prevent and treat blood circulation diseases such as deep vein thrombosis, heart disease and stroke.

The common method for preparing (3S)-3-aminopiperidin-2-one is through the reaction of cyclopentanedione and an amphoteric nucleophile (such as an amine compound). Among them, the selective preparation of (S)-3-amino-2-piperidone (I. e., a stereoisomer having a specific configuration) can be carried out by the control of a selective catalyst.

Regarding safety information, the specific toxicity and harmfulness of (3S)-3-aminopiperidin-2-one need to be further studied and verified. Follow laboratory practices and safe operating procedures, wear appropriate protective equipment to protect the skin, eyes and respiratory tract, and avoid contact and inhalation of the substance. In case of accidental contact, rinse immediately with plenty of water and seek medical help if necessary.

Last Update：2024-04-09 20:02:46