(S)-3-chloro-1,2-propanediol acetonide - Names and Identifiers
Name | (S)-3-chloro-1,2-propanediol acetonide
|
Synonyms | S-Chloropropanediol acetonide (S)-3-CHLORO-1,2-PROPANEDIOL ACETONIDE (S)-3-chloro-1,2-propanediol acetonide (S)-(-)-3-CHLORO-1,2-PROPANEDIOL ACETONIDE (S)-(-)-3-Chloro-1,2-propanediol acetonide (S)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE (S)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE (S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane (S)-(-)-4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE 1,3-DIOXOLANE, 4-(CHLOROMETHYL)-2,2-DIMETHYL-, (4S)-
|
CAS | 60456-22-6
|
EINECS | 628-358-9 |
InChI | InChI=1/C3H7ClO2.C3H5O/c4-1-3(6)2-5;1-3(2)4/h3,5-6H,1-2H2;1H2,2H3/q;-1/t3-;/m1./s1 |
InChIKey | BNPOTXLWPZOESZ-RXMQYKEDSA-N |
(S)-3-chloro-1,2-propanediol acetonide - Physico-chemical Properties
Molecular Formula | C6H11ClO2
|
Molar Mass | 150.6 |
Density | 1.103g/mLat 25°C(lit.) |
Boling Point | 63°C37mm Hg(lit.) |
Specific Rotation(α) | -42 º (neat 24 ºC) |
Flash Point | 123°F |
Appearance | clear liquid |
Specific Gravity | 1.103 |
Color | Colorless to Almost colorless |
BRN | 7409638 |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | n20/D 1.434(lit.) |
(S)-3-chloro-1,2-propanediol acetonide - Risk and Safety
Risk Codes | R10 - Flammable
R41 - Risk of serious damage to eyes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R25 - Toxic if swallowed
|
Safety Description | S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39 - Wear suitable gloves and eye/face protection
S36/39 -
|
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
RTECS | JH6950000 |
HS Code | 29329990 |
Hazard Class | 3 |
Packing Group | III |
(S)-3-chloro-1,2-propanediol acetonide - Introduction
(S)-3-chloro-1,2-propanediol acetonide is an organic compound with the chemical formula C7H11ClO3. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: It is a colorless to slightly yellow liquid.
-Melting point/boiling point: The melting point is about 60-70°C, and the boiling point is about 235-240°C.
-Solubility: It has low solubility in water, but has good solubility in organic solvents (such as alcohols, ethers, etc.).
Use:
-As a synthetic intermediate:(S)-3-choro-1, 2-propanediol acetonide can be used as an intermediate for the synthesis of other organic compounds, such as drugs, pesticides, etc.
-Protective agent for chemical reactions: It can be used as a hydroxyl protective agent to protect alcohol and carboxylic acid groups to prevent them from being changed in chemical reactions.
Preparation Method:
Generally,(S)-3-chloro-1,2-propanediol acetonide can be prepared by the following steps:
1. First, propylene glycol is reacted with hydrogen chloride to generate 3-chloro-1, 2-propanediol.
2. Then, the generated 3-chloro-1,2-propanediol is reacted with acetonide to generate the target product (S)-3-chloro-1,2-propanediol acetonide.
Safety Information:
- (S)-3-choro-1, 2-propanediol acetonide is a flammable liquid, avoid contact with high temperature and open flame.
-It is a harmful substance that may cause acute and chronic toxicity to the organism. After contact with skin, eyes, respiratory tract or taking, should be washed immediately, if necessary, seek medical help.
-When using or storing, take necessary safety measures, use appropriate personal protective equipment, and maintain a well-ventilated working environment.
-Follow local environmental regulations when handling and disposing of waste.
Last Update:2024-04-09 21:01:54