(S)-4-(羟甲基)-2,2-二甲基恶唑烷-3-甲酸叔丁酯

(S)-4-(羟甲基)-2,2-二甲基恶唑烷-3-甲酸叔丁酯 - Names and Identifiers

Name	(S)-4-Hydroxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester
Synonyms	(S)-1-Boc-2,2-DiMethyl-4-hydroxyMethyl-oxazolidine (S)-3-Boc-4-(hydroxymethyl)-2,2-dimethyl-1,3-oxazolidine tert-Butyl (S)-4-(Hydroxymethyl)-2,2-dimethyloxazolidine-3-carboxylate (S)-tert-butyl 4-(hydroxymethyl)-2,2-dimethyloxazolidine-3-carboxylate (S)-3-(tert-Butoxycarbonyl)-4-(hydroxymethyl)-2,2-dimethyl-1,3-oxazolidine tert-butyl (4S)-4-(hydroxymethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate (S)-4-Hydroxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 3-Oxazolidinecarboxylic acid, 4-(hydroxymethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-
CAS	108149-65-1
InChI	InChI=1/C11H21NO4/c1-10(2,3)16-9(14)12-8(6-13)7-15-11(12,4)5/h8,13H,6-7H2,1-5H3/t8-/m0/s1

(S)-4-(羟甲基)-2,2-二甲基恶唑烷-3-甲酸叔丁酯 - Physico-chemical Properties

Molecular Formula	C11H21NO4
Molar Mass	231.29
Density	1.075±0.06 g/cm3(Predicted)
Melting Point	36 °C
Boling Point	314.1±27.0 °C(Predicted)
Flash Point	143.745°C
Vapor Presure	0mmHg at 25°C
pKa	14.54±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.464

(S)-4-(羟甲基)-2,2-二甲基恶唑烷-3-甲酸叔丁酯 - Introduction

(S)-tert-butyl 4-hydroxymethyl-2, 2-dimethyloxazolidine-3-carboxylate is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
(S)-tert-butyl 4-hydroxymethyl-2, 2-dimethyloxazolidine-3-carboxylate is a colorless to pale yellow clear liquid. It has low volatility and relatively high stability at room temperature. The compounds have low solubility and are soluble in organic solvents such as ethers and esters.

Use:
The compound has important application value in the field of organic synthesis. As a chiral reagent, it is often used to catalyze asymmetric synthesis reactions for the preparation of chiral compounds. In addition, it can also be used as an intermediate for some drugs, such as lead compounds for the synthesis of some chiral drugs.

Preparation Method:
The preparation method of (S)-4-hydroxymethyl-2, 2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester is usually obtained by reacting the corresponding acid chloride with (S)-(-)-2,2-dimethyloxazolidine-3-methanol.

Safety Information:
This is a chemical, the operator should pay attention to safety. It may cause irritation to the eyes and skin and may cause damage to the respiratory system. During use, contact with skin and eyes should be avoided, and protective glasses and gloves should be worn if necessary. At the same time, it should be used in a well-ventilated place and avoid inhaling its gas or vapor. In case of inhalation or skin contact, rinse immediately with water and seek medical attention.

Last Update：2024-04-09 21:11:58