(S)-tert-Butyl (1-(3-chlorophenyl)-2-hydroxyethyl)carbamate - Names and Identifiers
Name | Carbamic acid, N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester
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Synonyms | (S)-tert-Butyl (1-(3-chlorophenyl)-2-hydroxyethyl)carbamate Carbamic acid, N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-, ... carbamic acid,[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-,1,1-dimethylethyl ester CarbaMic acid, N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester Carbamic acid, N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester
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CAS | 1379546-46-9
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(S)-tert-Butyl (1-(3-chlorophenyl)-2-hydroxyethyl)carbamate - Physico-chemical Properties
Molecular Formula | C13H18ClNO3
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Molar Mass | 271.74 |
Storage Condition | 2-8°C |
(S)-tert-Butyl (1-(3-chlorophenyl)-2-hydroxyethyl)carbamate - Introduction
(S)-B-(Boc-amino)-3-chlorophenethanol is an organic compound with the following properties:
1. Appearance: white crystalline solid
2. molecular formula: C13H17ClNO3
3. Molecular weight: 271.7g/mol
Use of (S)-B-(Boc-amino)-3-chlorophenylethyl alcohol:
This compound is often used in some important reactions in the field of organic synthesis, mainly for the synthesis of biologically active compounds, such as pharmaceutical intermediates and chiral ligands. In addition, it can also be used as a chiral inducer to catalyze asymmetric reactions.
Preparation Method:
The preparation method of (S)-B-(Boc-amino)-3-chlorophenethanol is as follows:
First, (3-chlorophenyl)-[(1,1-dimethylethylamino) (amino) methyl]-methanol is reacted with N-tert-butoxycarbonyl oxime in an appropriate solvent to obtain a double bond ketone, and then the double bond ketone is reduced to (S)-B-(Boc-amino)-3-chlorophenethanol by a reduction reaction.
Safety Information:
During operation, it is necessary to pay attention to the toxicity and irritation of the compound, and appropriate protective equipment should be worn to avoid contact with skin and eyes. At the same time, it is necessary to operate in a well-ventilated place to avoid inhaling aerosol-like substances. If ingestion or skin contact occurs, seek medical attention immediately and bring the compound's safety data sheet with you.
Last Update:2024-04-09 21:11:58