1(2H)-Isoquinolinone, 6-amino-
6-Aminoisoquinolin-1(2H)-one
CAS: 216099-46-6
Molecular Formula: C9H8N2O
1(2H)-Isoquinolinone, 6-amino- - Names and Identifiers
| Name | 6-Aminoisoquinolin-1(2H)-one |
| Synonyms | 6-Aminoisoquinolin-1-ol 6-amino-2H-isoquinolin-1-one 6-Aminoisoquinolin-1(2H)-one 6-AMino-1(2H)-Isoquinolinone 1(2H)-Isoquinolinone, 6-amino- 6-amino-1,2-dihydroisoquinolin-1-one 1-Oxoisoquinolin-6-amine, 6-Aminoisoquinolin-1-ol |
| CAS | 216099-46-6 |
| InChI | InChI=1S/C9H8N2O/c10-7-1-2-8-6(5-7)3-4-11-9(8)12/h1-5H,10H2,(H,11,12) |
1(2H)-Isoquinolinone, 6-amino- - Physico-chemical Properties
| Molecular Formula | C9H8N2O |
| Molar Mass | 160.17 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Irritant |
| MDL | MFCD12547311 |
1(2H)-Isoquinolinone, 6-amino- - Introduction
6-Aminoisoquinolin-1(2H)-one is an organic compound with the chemical formula C10H8N2O. It is a white solid with a strong ammonia-musty odor.
The compound has a wide range of applications in the pharmaceutical and chemical fields. The most common application is as an intermediate in organic synthesis. It can be used to synthesize various drugs and compounds, such as anticancer drugs, immunomodulators, etc.
The preparation method of 6-Aminoisoquinolin-1(2H)-one can be obtained by The nitration reaction of isoquinoline. First, isoquinoline is mixed with nitric acid and reacted at low temperature to form nitroisoquinoline. The nitroisoquinoline is then reduced using hydrogen and a platinum catalyst to form 6-Aminoisoquinolin-1(2H)-one.
Regarding safety information, 6-Aminoisoquinolin-1(2H)-one has low toxicity, but as a chemical substance, it still needs to follow safe operating regulations. Avoid inhalation, skin contact or ingestion during operation. Wear appropriate protective equipment such as protective gloves and goggles. Any work should be done in a well-ventilated area. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In handling, storage and disposal, should follow the relevant safety regulations and laws and regulations.
The compound has a wide range of applications in the pharmaceutical and chemical fields. The most common application is as an intermediate in organic synthesis. It can be used to synthesize various drugs and compounds, such as anticancer drugs, immunomodulators, etc.
The preparation method of 6-Aminoisoquinolin-1(2H)-one can be obtained by The nitration reaction of isoquinoline. First, isoquinoline is mixed with nitric acid and reacted at low temperature to form nitroisoquinoline. The nitroisoquinoline is then reduced using hydrogen and a platinum catalyst to form 6-Aminoisoquinolin-1(2H)-one.
Regarding safety information, 6-Aminoisoquinolin-1(2H)-one has low toxicity, but as a chemical substance, it still needs to follow safe operating regulations. Avoid inhalation, skin contact or ingestion during operation. Wear appropriate protective equipment such as protective gloves and goggles. Any work should be done in a well-ventilated area. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In handling, storage and disposal, should follow the relevant safety regulations and laws and regulations.
Last Update：2024-04-09 21:01:54
