1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose

1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose - Names and Identifiers

Name	1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose
Synonyms	Topiramate Impurity 2 1,3,4,5,6-pentahydroxy-2-hexanone 4,5-Di-O-isopropylidene-b-D-fructopyranose (3aR,4'S,7S,7aS)-2,2,2',2'-tetraMethyltetrahydrospiro[[1,3]dioxolo[4,5-c]pyran-6,4'-[1,3]dioxolan]-7-ol
CAS	25018-67-1

1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose - Physico-chemical Properties

Molecular Formula	C12H20O6
Molar Mass	260.28
Density	1.28±0.1 g/cm3(Predicted)
Melting Point	116-117 °C
Boling Point	379.0±42.0 °C(Predicted)
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Solid
Color	Light Brown
pKa	13.88±0.60(Predicted)
Storage Condition	Refrigerator

1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose - Introduction

1,2: 4,5-di-O-isopropylidene-beta-D-fructopyranose is a chemical compound, also known as diisopropyldiisothionide.

Nature:
1,2: 4,5-di-O-isopropylidene-beta-D-fructopyranose is a white crystalline solid, soluble in water and alcohol. It is a derivative of sugar and has the characteristics of sugar, that is, it has a high sweetness.

Use:
1,2: 4,5-di-O-isopropylidene-beta-D-fructopyranose plays an important role in organic chemical synthesis. It is often used as a protecting group to protect hydroxyl or amine groups to avoid accidental chemical reactions during the reaction. By adding a 1,2: 4,5-di-O-isopropylidene group, the hydroxyl group in the saccharide can be protected to enable selective reaction if desired.

Method:
1,2: 4,5-di-O-isopropylidene-beta-D-fructopyranose is synthesized by reaction with isopropanol under acidic conditions. This reaction produces a 1,2-isopropyl group, forming a 1,2: 4,5-di-O-isopropylidene group protecting the hydroxyl group.

Safety Information:
There is no detailed research report on the safety of 1,2: 4,5-di-O-isopropylidene-beta-D-fructose pyranopyranose. However, it is generally considered to be of low toxicity and is widely used in many laboratories. However, in any chemical experiment, the correct experimental operation and laboratory safety measures are necessary. When using 1,2: 4,5-di-O-isopropylidene-beta-D-fructopyranose, care should be taken to avoid contact with skin, eyes and respiratory tract. In case of accidental contact, flush with water immediately and seek medical assistance.

Last Update：2024-04-09 21:54:55