1,2,3,4-tetrahydro-4-oxo-1-naphthalenecarboxylic acid
4-Oxo-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid
CAS: 3123-46-4
Molecular Formula: C11H10O3
1,2,3,4-tetrahydro-4-oxo-1-naphthalenecarboxylic acid - Names and Identifiers
1,2,3,4-tetrahydro-4-oxo-1-naphthalenecarboxylic acid - Physico-chemical Properties
| Molecular Formula | C11H10O3 |
| Molar Mass | 190.2 |
| Density | 1.311±0.06 g/cm3(Predicted) |
| Melting Point | 93-95 °C |
| Boling Point | 379.9±41.0 °C(Predicted) |
| pKa | 3.97±0.20(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD00177946 |
1,2,3,4-tetrahydro-4-oxo-1-naphthalenecarboxylic acid - Risk and Safety
| Hazard Class | IRRITANT |
1,2,3,4-tetrahydro-4-oxo-1-naphthalenecarboxylic acid - Introduction
4-Oxo-1,2,3, acid is an organic compound whose chemical formula is C11H10O3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 4-Oxo-1,2,3, and acid are white crystalline solids.
-Melting point: The melting point of the compound is 179-183 degrees Celsius.
-Solubility: 4-Oxo-1,2,3,-acid is soluble in some organic solvents, such as ethanol or chloroform.
Use:
-Laboratory research: 4-Oxo-1,2,3, 15-acid can be used as a starting material or transition compound in organic synthesis reactions.
-Pharmaceutical research: The compound may have some potential biological activities in the pharmaceutical field, so it can be used for pharmaceutical research and development.
Preparation Method:
The preparation method of 4-Oxo-1,2,3, acid can be realized by the following steps:
-First, 4-oxo-2, 3-dihydro-1H-naphthalene (a commonly used intermediate) is reacted with an oxygenating agent (such as benzoyl peroxide) to generate 4-oxo-2, 3-Dihydro-1H-naphthalen-1-one.
-Next, 4-oxo-2, 3-dihydro-1H-naphthalen-1-one is reacted with hydrochloric acid to generate 4-oxo-2, 3-dihydro-1H-naphthalene-1-carboxylic acid.
-Finally, remove the water by heating and slowly volatilizing the solvent, and obtain 4-Oxo-1,2,3, acid from 4-oxo-2, 3-dihydro-1H-naphthalene-1-carboxylic acid.
Safety Information:
- 4-Oxo-1,2,3, the toxicity and danger of acid have not been clearly reported, but when handling, it is recommended to wear appropriate protective equipment, such as gloves and laboratory nasal masks.
-The compound may be irritating to the eyes and skin, so contact with the eyes and skin should be avoided.
-When storing and handling, please observe the relevant safety procedures and ensure that the laboratory environment is well ventilated.
Nature:
-Appearance: 4-Oxo-1,2,3, and acid are white crystalline solids.
-Melting point: The melting point of the compound is 179-183 degrees Celsius.
-Solubility: 4-Oxo-1,2,3,-acid is soluble in some organic solvents, such as ethanol or chloroform.
Use:
-Laboratory research: 4-Oxo-1,2,3, 15-acid can be used as a starting material or transition compound in organic synthesis reactions.
-Pharmaceutical research: The compound may have some potential biological activities in the pharmaceutical field, so it can be used for pharmaceutical research and development.
Preparation Method:
The preparation method of 4-Oxo-1,2,3, acid can be realized by the following steps:
-First, 4-oxo-2, 3-dihydro-1H-naphthalene (a commonly used intermediate) is reacted with an oxygenating agent (such as benzoyl peroxide) to generate 4-oxo-2, 3-Dihydro-1H-naphthalen-1-one.
-Next, 4-oxo-2, 3-dihydro-1H-naphthalen-1-one is reacted with hydrochloric acid to generate 4-oxo-2, 3-dihydro-1H-naphthalene-1-carboxylic acid.
-Finally, remove the water by heating and slowly volatilizing the solvent, and obtain 4-Oxo-1,2,3, acid from 4-oxo-2, 3-dihydro-1H-naphthalene-1-carboxylic acid.
Safety Information:
- 4-Oxo-1,2,3, the toxicity and danger of acid have not been clearly reported, but when handling, it is recommended to wear appropriate protective equipment, such as gloves and laboratory nasal masks.
-The compound may be irritating to the eyes and skin, so contact with the eyes and skin should be avoided.
-When storing and handling, please observe the relevant safety procedures and ensure that the laboratory environment is well ventilated.
Last Update：2024-04-09 21:01:54
