1,2-二(顺式-9,12-十八二烯酰基)-SN-甘油-3-磷酸胆碱

1,2-二(顺式-9,12-十八二烯酰基)-SN-甘油-3-磷酸胆碱 - Names and Identifiers

Name	1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms	L-ALPHA-Dilinoleoylphosphatidyl choline 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE L-A-PHOSPHATIDYLCHOLINE DILINOLEOYL SYNTHETIC L-A-PHOSPHATIDYLCHOLINE DILINOLEOYL,*LYO PHILIZED 1,2-DI9-CIS-12-CIS-OCTADECENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DI[CIS-9,12-OCTADECADIENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE [R-(all-Z)]-[4-oxido-10-oxo-7-[(1-oxooctadeca-9,12-dienyl)oxy]-3,5,9-trioxa-4-phosphaheptacosa-18,21-dienyl]trimethylammonium 4-oxide
CAS	998-06-1
EINECS	213-647-0

1,2-二(顺式-9,12-十八二烯酰基)-SN-甘油-3-磷酸胆碱 - Physico-chemical Properties

Molecular Formula	C44H80NO8P
Molar Mass	782.08
Appearance	lyophilized powder
Storage Condition	-20°C

1,2-二(顺式-9,12-十八二烯酰基)-SN-甘油-3-磷酸胆碱 - Risk and Safety

WGK Germany	1
FLUKA BRAND F CODES	1-8-10

1,2-二(顺式-9,12-十八二烯酰基)-SN-甘油-3-磷酸胆碱 - Upstream Downstream Industry

Raw Materials

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol
LINOLEOYL CHLORIDE
(S)-2,3-Bis(linoleoyloxy)-1-propanol
Linoleic acid
Trimethylamine
Choline chloride
2-Chloroethanol

1,2-二(顺式-9,12-十八二烯酰基)-SN-甘油-3-磷酸胆碱 - Introduction

1, is a phospholipid compound consisting of 1,2-dilinoleic acid (also known as 1,2-dilinoleic acid glycerophosphorylcholine) and the phosphate group of glycerides.

DLinPC is a colorless or light yellow solid that can form lipid nanoparticles and is soluble in organic solvents (such as chloroform, methanol) and fat-soluble solutions.

DLinPC is widely used in drug delivery and gene transfection. It is a commonly used carrier that can be used to encapsulate and deliver drugs, genes and other biologically active molecules. The linoleic acid group in the DLinPC structure provides flexibility and moderate mobility to facilitate efficient drug delivery and gene transfection.

One of the main methods for preparing DLinPC is through a synthetic method, usually starting from linoleic acid, through a series of reactions such as esterification and phosphorylation to obtain the target product. The specific steps and conditions of the preparation will vary depending on the needs of the laboratory and the scale of preparation.

About DLinPC safety information, excessive contact or ingestion may cause irritation, should avoid inhalation of dust. For specific use and storage information, refer to the safety data sheets provided by the manufacturer or consult a professional for advice. Appropriate laboratory safety practices and personal protective measures must be followed when using DLinPC.

Last Update：2024-04-09 21:54:55