1,2-Cyclobutanedimethanamine, (1R,2R)-rel-

1,2-Cyclobutanedimethanamine, (1R,2R)-rel- - Names and Identifiers

Name	trans-1,2-Bis(aminomethyl)cyclobutane
Synonyms	1,2-Bis(aminomethyl)cyclobutane trans-1,2-Bis(aminomethyl)cyclobutane trans-1,2-Bis(aminomethyl)cyclobutene [2-(aminomethyl)cyclobutyl]methanamine [2-(aminomethyl)cyclobutyl]methylamine (trans)-cyclobutane-1,2-diyldimethanamine 1,2-Cyclobutanedimethanamine, (1R,2R)-rel- [(1R,2R)-2-(Aminomethyl)cyclobutyl]methylamine rel-[(1R,2R)-2-(Aminomethyl)cyclobutyl]methylamine
CAS	1731-23-3

1,2-Cyclobutanedimethanamine, (1R,2R)-rel- - Physico-chemical Properties

Molecular Formula	C6H14N2
Molar Mass	114.19
Density	0.947±0.06 g/cm3(Predicted)
Boling Point	80-82 °C(Press: 10 Torr)
pKa	10.57±0.29(Predicted)

1,2-Cyclobutanedimethanamine, (1R,2R)-rel- - Introduction

trans-1,2-Bis(aminomethyl) cyclobutyane is an organic compound with the chemical formula C6H14N2. It has two aminomethyl groups (-CH2NH2) and one cyclobutylin (C4H6) in its structure. The following is a description of some properties, uses, preparation and safety information about the compound:

Nature:
- trans-1, the molecular formula of 2-Bis(aminomethyl)cyclobutane is C6H14N2, and the relative molecular mass is 114.19g/mol.
-It is a colorless to light yellow liquid with a pungent odor.
-It has a density of 0.879 g/mL and is almost insoluble in water at room temperature, but soluble in many organic solvents such as alcohols and ethers.
-its boiling point is 196-197 ℃, and can be distilled to separate higher purity products.

Use:
- trans-1,2-Bis(aminomethyl)cyclobutane can be used as an intermediate in organic synthesis and is often used in the synthesis of drugs and other biologically active molecules.
-It can also be used to prepare ligands with specific structures and functions for the synthesis of catalysts and coordination compounds.

Method:
- trans-1,2-Bis(aminomethyl)cyclobutane is generally synthesized by reacting a carbon-to-carbon double bond. A common preparation method is the reaction of 1,2-cyclobutanediamine with formaldehyde (formaldehyde), which undergoes a polycondensation reaction to produce trans-1,2-Bis(aminomethyl)cyclobutane.

Safety Information:
- trans-1,2-Bis(aminomethyl) cyclostatin has a certain degree of irritation and may cause irritation and inflammation after contact with skin and eyes. Therefore, care should be taken to avoid contact with skin and eyes, and use appropriate protective measures, such as wearing gloves, goggles and laboratory coats.
-When using or storing trans-1,2-Bis(aminomethyl) cycloputane, keep a well-ventilated environment and avoid contact with strong oxidants and other substances, to prevent chemical reactions or dangerous situations.
-In case of accidental inhalation or ingestion, seek medical attention immediately and bring the compound's MSDS (safety data sheet) to the hospital.

Last Update：2024-04-09 20:48:19