1,2-DIMETHYL-1H-IMIDAZOLE-4-SULFONYL CHLORIDE - Names and Identifiers
1,2-DIMETHYL-1H-IMIDAZOLE-4-SULFONYL CHLORIDE - Physico-chemical Properties
Molecular Formula | C5H7ClN2O2S
|
Molar Mass | 194.64 |
Density | 1.52±0.1 g/cm3(Predicted) |
Melting Point | 91 °C |
Boling Point | 357.5±15.0 °C(Predicted) |
Flash Point | 170°C |
Vapor Presure | 5.59E-05mmHg at 25°C |
pKa | 1.18±0.70(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Stability | Moisture Sensitive, Hygroscopic |
Refractive Index | 1.605 |
1,2-DIMETHYL-1H-IMIDAZOLE-4-SULFONYL CHLORIDE - Risk and Safety
Risk Codes | 34 - Causes burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
UN IDs | 3261 |
Hazard Class | MOISTURE SENSITIVE, |
1,2-DIMETHYL-1H-IMIDAZOLE-4-SULFONYL CHLORIDE - Introduction
1,2-Dimethyl-1H-imidazole-4-sulfonyl chloride is an organic compound with the chemical formula C5H7ClN2O2S. The following is a description of its nature, use, formulation and safety information:
Nature:
1,2-dimethyl-1H-imidazole-4-sulfonyl chloride is a colorless to light yellow oily liquid with a strong pungent odor. It is insoluble in water but miscible with organic solvents such as dichloromethane, ether and methanol. Its boiling point is about 107°C.
Use:
1,2-dimethyl-1H-imidazole-4-sulfonyl chloride is an important intermediate compound. It can be used to synthesize drugs that lower blood sugar in diabetics. In addition, it is also used in the synthesis of pesticides, dyes and other organic compounds.
Preparation Method:
1,2-Dimethyl-1H-imidazole-4-sulfonyl chloride can be synthesized by the following steps:
1. First, sodium 1,2-dimethyl -1H-imidazole-4-sulfonyl chloride is reacted with a nitroso compound to generate nitrosimidazole sulfonate.
2. Then, the nitrosimidazole sulfonate is reacted with sulfuryl chloride to generate 1,2-dimethyl-1H-imidazole-4-sulfonyl chloride.
Safety Information:
1,2-Dimethyl-1H-imidazole-4-sulfonyl chloride is irritating and corrosive. Wear appropriate protective gloves, glasses and protective clothing when in use, and ensure that the operation is carried out in a well-ventilated place. In case of contact with skin or eyes, rinse immediately with plenty of water. Avoid inhaling its vapors and, if necessary, operate under ventilation systems with exhaust equipment. In addition, it should be stored in a dark, dry, sealed container, and away from fire and heat sources.
Last Update:2024-04-09 21:01:54