1,3,5(10)Estatrien-2,3-diol-17-one
2-Hydroxy Estrone
CAS: 362-06-1
Molecular Formula: C18H22O3
1,3,5(10)Estatrien-2,3-diol-17-one - Names and Identifiers
1,3,5(10)Estatrien-2,3-diol-17-one - Physico-chemical Properties
| Molecular Formula | C18H22O3 |
| Molar Mass | 286.37 |
| Density | 1.241±0.06 g/cm3(Predicted) |
| Melting Point | 199-201°C |
| Boling Point | 481.3±45.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | Off-White to Light Brown |
| pKa | 10.10±0.40(Predicted) |
| Storage Condition | -20°C Freezer |
1,3,5(10)Estatrien-2,3-diol-17-one - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 40 - Limited evidence of a carcinogenic effect |
| Safety Description | S22 - Do not breathe dust. S36 - Wear suitable protective clothing. |
| UN IDs | UN 1648 3 / PGII |
1,3,5(10)Estatrien-2,3-diol-17-one - Introduction
2-Hydroxy Estrone(2-Hydroxy Estrone) is one of the metabolites of the estrogen estradiol. It is a white crystalline solid that is stable at room temperature. 2-Hydroxy Estrone is produced in organisms and is mainly produced by the liver when it metabolizes estrogen.
2-Hydroxy Estrone has some important applications in medical and biochemical research. It is considered to be a marker of estrogen metabolism and can be used to assess the rate of estrogen metabolism and the risk of estrogen-related diseases. In addition, 2-Hydroxy Estrone is also used as a monitoring indicator for hormone therapy, such as monitoring the therapeutic effect of breast cancer.
The method of preparing 2-Hydroxy Estrone is mainly through in vitro synthesis or catalytic reaction of endogenous enzymes. Methods of in vitro synthesis generally involve isolation and identification from biological samples by high performance liquid chromatography (HPLC). Endogenous synthesis involves specific enzymes and metabolic pathways.
Regarding safety information, 2-Hydroxy Estrone is considered relatively safe at regular doses. However, excessive use may lead to side effects of too much estrogen, such as an increased risk of hormone-dependent tumors. When using 2-Hydroxy Estrone, the advice of a doctor or professional should be followed, and regular monitoring and evaluation should be carried out. If you have any discomfort or doubts, you should consult your doctor in time.
2-Hydroxy Estrone has some important applications in medical and biochemical research. It is considered to be a marker of estrogen metabolism and can be used to assess the rate of estrogen metabolism and the risk of estrogen-related diseases. In addition, 2-Hydroxy Estrone is also used as a monitoring indicator for hormone therapy, such as monitoring the therapeutic effect of breast cancer.
The method of preparing 2-Hydroxy Estrone is mainly through in vitro synthesis or catalytic reaction of endogenous enzymes. Methods of in vitro synthesis generally involve isolation and identification from biological samples by high performance liquid chromatography (HPLC). Endogenous synthesis involves specific enzymes and metabolic pathways.
Regarding safety information, 2-Hydroxy Estrone is considered relatively safe at regular doses. However, excessive use may lead to side effects of too much estrogen, such as an increased risk of hormone-dependent tumors. When using 2-Hydroxy Estrone, the advice of a doctor or professional should be followed, and regular monitoring and evaluation should be carried out. If you have any discomfort or doubts, you should consult your doctor in time.
Last Update：2024-04-09 20:52:54
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CAS: 362-06-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 362-06-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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