1,3-Azetidinedicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester
1-tert-butyl 3-methyl azetidine-1,3-dicarboxylate
CAS: 610791-05-4
Molecular Formula: C10H17NO4
1,3-Azetidinedicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester - Names and Identifiers
1,3-Azetidinedicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester - Physico-chemical Properties
| Molecular Formula | C10H17NO4 |
| Molar Mass | 215.25 |
| Density | 1.072 g/mL at 25 °C |
| Boling Point | 269.0±33.0 °C(Predicted) |
| Flash Point | >110℃ |
| Vapor Presure | 0.00743mmHg at 25°C |
| pKa | -2.97±0.40(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | n20/D1.452 |
1,3-Azetidinedicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
1,3-Azetidinedicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester - Introduction
1-tert-butyl 3-methyl azetidine-1,3-dicarboxylate, also known as 1-tert-butyl 3-methyl azetidine-1,3-dicarboxylate, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless liquid or crystalline solid
-Molecular formula: C11H19NO4
-Molecular weight: 233.27g/mol
-Melting point: about 45-47°C
-Boiling point: about 229°C
-Solubility: Good solubility in some organic solvents (such as ethanol and dichloromethane)
Use:
- 1-tert-butyl 3-methyl azetidine-1,3-dicarboxylate is widely used in organic synthesis, especially in the field of medicine. It is often used as an intermediate and as a protecting group.
Preparation Method:
- 1-tert-butyl 3-methyl azetidine-1, the preparation method of 3-dicarboxylate is more complicated. A common synthetic method is to introduce the Boc protecting group by reacting azetidine with methyl formate followed by tert-Butyl chloroformate.
Safety Information:
- 1-tert-butyl 3-methyl azetidine-1,3-dicarboxylate is generally considered to be a relatively safe compound, but it still requires careful handling.
-Wear appropriate personal protective equipment, such as lab gloves and goggles.
-Avoid contact with skin and eyes. In case of contact, immediately flush the affected area with plenty of water and seek medical help.
-It should be used in a well-ventilated environment to avoid inhaling its vapor or dust.
-Keep the container tightly closed during storage and store it in a dry and dark place.
Nature:
-Appearance: Colorless liquid or crystalline solid
-Molecular formula: C11H19NO4
-Molecular weight: 233.27g/mol
-Melting point: about 45-47°C
-Boiling point: about 229°C
-Solubility: Good solubility in some organic solvents (such as ethanol and dichloromethane)
Use:
- 1-tert-butyl 3-methyl azetidine-1,3-dicarboxylate is widely used in organic synthesis, especially in the field of medicine. It is often used as an intermediate and as a protecting group.
Preparation Method:
- 1-tert-butyl 3-methyl azetidine-1, the preparation method of 3-dicarboxylate is more complicated. A common synthetic method is to introduce the Boc protecting group by reacting azetidine with methyl formate followed by tert-Butyl chloroformate.
Safety Information:
- 1-tert-butyl 3-methyl azetidine-1,3-dicarboxylate is generally considered to be a relatively safe compound, but it still requires careful handling.
-Wear appropriate personal protective equipment, such as lab gloves and goggles.
-Avoid contact with skin and eyes. In case of contact, immediately flush the affected area with plenty of water and seek medical help.
-It should be used in a well-ventilated environment to avoid inhaling its vapor or dust.
-Keep the container tightly closed during storage and store it in a dry and dark place.
Last Update：2024-04-09 15:17:58
