1,3-Thiazole-2-Carboxylic Acid
Thiazole-2-Carboxylic Acid
CAS: 14190-59-1
Molecular Formula: C4H3NO2S
1,3-Thiazole-2-Carboxylic Acid - Names and Identifiers
1,3-Thiazole-2-Carboxylic Acid - Physico-chemical Properties
| Molecular Formula | C4H3NO2S |
| Molar Mass | 129.14 |
| Density | 1.525±0.06 g/cm3(Predicted) |
| Melting Point | 91.6-93°C |
| Boling Point | 310.6±25.0 °C(Predicted) |
| Flash Point | 141.6°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.000256mmHg at 25°C |
| Appearance | Crystallization |
| pKa | 2.95±0.10(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.617 |
| MDL | MFCD02094169 |
1,3-Thiazole-2-Carboxylic Acid - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. |
| WGK Germany | 1 |
| HS Code | 29349990 |
1,3-Thiazole-2-Carboxylic Acid - Introduction
Thiazole-2-carboxylic acid is an organic compound with the chemical formula C4H3NO2S. The following is a description of the properties, uses, preparation and safety information of thiazole-2-carboxylic acid:
Nature:
-Appearance: White or almost white crystal
-Melting point: 158-160 degrees Celsius
-Solubility: Soluble in common organic solvents such as water, alcohol and ether
Use:
-Thiazole-2-carboxylic acid has a wide range of applications in the manufacture of pharmaceuticals and pesticides. It is used as a precursor for the synthesis of certain nitrothiazole drugs and as a starting material for certain methylmethionine decarboxylase inhibitors.
-It can also be used as a dye, catalyst in organic synthesis and advanced intermediate substances.
Preparation Method:
-Thiazole-2-carboxylic acid can be prepared in a variety of ways. One common method is by reacting 2-aminothiazole with methylene chloride to form thiazole-2-carboxylic acid chloride, which is then reacted with water to form thiazole-2-carboxylic acid.
Safety Information:
-Thiazole-2-carboxylic acid is generally considered safe under normal conditions of use.
-But it is an organic compound that may have a certain impact on human health. In contact with it, should avoid inhalation of dust and skin exposure. Wear appropriate protective equipment, such as gloves and goggles.
-When storing and handling thiazole-2-carboxylic acid, care should be taken to avoid contact with oxidants, strong acids and strong bases to prevent dangerous reactions.
Nature:
-Appearance: White or almost white crystal
-Melting point: 158-160 degrees Celsius
-Solubility: Soluble in common organic solvents such as water, alcohol and ether
Use:
-Thiazole-2-carboxylic acid has a wide range of applications in the manufacture of pharmaceuticals and pesticides. It is used as a precursor for the synthesis of certain nitrothiazole drugs and as a starting material for certain methylmethionine decarboxylase inhibitors.
-It can also be used as a dye, catalyst in organic synthesis and advanced intermediate substances.
Preparation Method:
-Thiazole-2-carboxylic acid can be prepared in a variety of ways. One common method is by reacting 2-aminothiazole with methylene chloride to form thiazole-2-carboxylic acid chloride, which is then reacted with water to form thiazole-2-carboxylic acid.
Safety Information:
-Thiazole-2-carboxylic acid is generally considered safe under normal conditions of use.
-But it is an organic compound that may have a certain impact on human health. In contact with it, should avoid inhalation of dust and skin exposure. Wear appropriate protective equipment, such as gloves and goggles.
-When storing and handling thiazole-2-carboxylic acid, care should be taken to avoid contact with oxidants, strong acids and strong bases to prevent dangerous reactions.
Last Update：2024-04-09 02:00:42
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CAS: 14190-59-1
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CAS: 14190-59-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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