1-(2-CHLORO-4-HYDROXY-PHENYL)-ETHANONE

1-(2-CHLORO-4-HYDROXY-PHENYL)-ETHANONE - Names and Identifiers

Name	4-Hydroxy-2-chloroacetophenone
Synonyms	MELU-001 4-Hydroxy-2-chloroacetophenone 4-HYDROXY-2-CHLOROACETOPHENONE 2'-chloro-4'-hydroxyacetophenone 2'-CHLORO-4'-HYDROXYACETOPHENONE 2'-Chloro-4'-hydroxyacetophenone 4'-HYDROXY-2'-CHLORO ACETOPHENONE 1-(2-Chlor-4-hydroxyphenyl)ethanon 1-(4-HYDROXY-2-CHLOROPHENYL)ETHANONE 1-(2-Chloro-4-hydroxyphenyl)ethanone 1-(2-CHLORO-4-HYDROXY-PHENYL)-ETHANONE 1-(2-Chloro-4-hydroxyphenyl)ethan-1-one ethanone, 1-(2-chloro-4-hydroxyphenyl)- 1-(2-Chloro-4-hydroxyphenyl)ethan-1-one, 4-Acetyl-3-chlorophenol
CAS	68301-59-7
InChI	InChI=1/C8H7ClO2/c1-5(10)7-3-2-6(11)4-8(7)9/h2-4,11H,1H3

1-(2-CHLORO-4-HYDROXY-PHENYL)-ETHANONE - Physico-chemical Properties

Molecular Formula	C8H7ClO2
Molar Mass	170.59
Density	1.298±0.06 g/cm3(Predicted)
Melting Point	110 °C
Boling Point	288.0±20.0 °C(Predicted)
Flash Point	128°C
Vapor Presure	0.00139mmHg at 25°C
Appearance	White solid
pKa	7.21±0.18(Predicted)
Storage Condition	2-8℃
Refractive Index	1.569

1-(2-CHLORO-4-HYDROXY-PHENYL)-ETHANONE - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

1-(2-CHLORO-4-HYDROXY-PHENYL)-ETHANONE - Introduction

It is an organic compound with the chemical formula C8H7ClO2. It is a white to light yellow solid with a special aroma. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White to light yellow crystalline solid.
-Solubility: It is soluble in alcohol and ketone solvents, insoluble in water.
-Melting point: The melting point range of the compound is 98-102°C.
-Stability: It is stable at room temperature, but may decompose in the presence of high temperature, light and oxygen.

Use:
-Chemical synthesis: It can be used as an important intermediate in organic synthesis and used to synthesize some biologically active compounds, such as drugs and pesticides.
-Drugs: This compound is also used to prepare certain drugs, such as anti-inflammatory drugs and anti-tumor drugs.
-Cosmetics: It is also used in some cosmetics to increase its aroma and improve texture.

Preparation Method: The preparation of
-phosphonate is usually carried out by the reaction of acetone acetate and chloroacetic acid in the presence of an acid catalyst. The reaction conditions include the appropriate temperature and time to yield the final product.

Safety Information:
-is a chemical substance that should be handled in accordance with correct laboratory operations and safety measures.
-It may be irritating to the eyes, skin and respiratory system, so care should be taken to avoid direct contact during operation.
-It should be operated in a well-ventilated place to avoid the accumulation of harmful gases.
-When using and storing it, keep it away from flammable materials and strong oxidants.
-When handling the compound, comply with relevant regulations and safety measures, such as wearing protective gloves, eye protection and respiratory protection equipment.

Last Update：2024-04-09 20:49:11