1-(2-chloroethyl)imidazolidin-2-one - Names and Identifiers
1-(2-chloroethyl)imidazolidin-2-one - Physico-chemical Properties
Molecular Formula | C5H9ClN2O
|
Molar Mass | 148.59 |
Density | 1.225±0.06 g/cm3(Predicted) |
Melting Point | 85-85 °C(Solv: acetone (67-64-1); carbon tetrachloride (56-23-5)) |
Boling Point | 347.5±21.0 °C(Predicted) |
Flash Point | 164°C |
Vapor Presure | 5.36E-05mmHg at 25°C |
pKa | 14.31±0.20(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.489 |
1-(2-chloroethyl)imidazolidin-2-one - Risk and Safety
1-(2-chloroethyl)imidazolidin-2-one - Introduction
1-(2-chloroethyl)imidazolidin-2-one is an organic compound with the chemical formula C6H10ClN2O. The following is a description of its nature, use, preparation and safety information:
Nature:
1-(2-chloroethyl)imidazolidin-2-one is a colorless to light yellow solid with a special nitrogen heterocyclic structure. It is stable at room temperature and not easily hydrolyzed. It is insoluble in water, but soluble in organic solvents such as ethanol, ether and chlorinated hydrocarbons.
Use:
1-(2-chloroethyl)imidazolidin-2-one has antibacterial and bactericidal properties, so it can be used in the medical field. Its antibacterial properties can be used in the production of antibacterial agents, preservatives and bactericides. In addition, it is also used in the synthesis of other organic compounds, such as rubber vulcanization accelerators, dye intermediates, etc.
Method:
The preparation method of 1-(2-chloroethyl)imidazolidin-2-one can be obtained by the reaction of 2-chloroethylamine and carbon dioxide. A specific synthetic route may be that 2-chloroethylamine and sodium hydroxide are reacted at a high temperature to obtain 2-chloroethylamine, and then reacted with carbon dioxide in the presence of sodium carbonate to generate 4-chloroacetamide. Finally, 4-chloroacetamide is reacted with a high concentration of aqueous ammonia to produce 1-(2-chloroethyl)imidazolidin-2-one.
Safety Information:
1-(2-chloroethyl)imidazolidin-2-one is an organic compound and should comply with safe operating procedures. In case of contact with skin, eyes or respiratory tract, rinse immediately with plenty of water and seek medical attention. Avoid fire, high temperature and open fire during use or storage. In addition, it should also be kept away from organics and oxidants to avoid dangerous reactions. Wear appropriate personal protective equipment such as lab gloves, goggles and protective masks during use.
Last Update:2024-04-09 21:00:56