1-(4-bromo-2-chlorophenyl)cyclopropan-1-amine hydrochloride - Names and Identifiers
1-(4-bromo-2-chlorophenyl)cyclopropan-1-amine hydrochloride - Physico-chemical Properties
| Molecular Formula | C9H9BrClN
|
| Molar Mass | 246.53 |
| Density | 1.626±0.06 g/cm3(Predicted) |
| Boling Point | 295.2±40.0 °C(Predicted) |
| pKa | 7.03±0.20(Predicted) |
1-(4-bromo-2-chlorophenyl)cyclopropan-1-amine hydrochloride - Introduction
1-(4-bromo-2-chlorophenyl)cyclopropan-1-amine is an organic compound with the chemical formula C9H10BrClN HCl. The following is its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless or white crystalline powder
-Melting point: About 250-253 ° C
-Solubility: Good solubility in water
-Molecular weight: 309.51g/mol
Use:
- 1-(4-bromo-2-chlorophenyl)cyclopropan-1-amine is commonly used as an intermediate in organic synthesis to synthesize other compounds, such as drugs, dyes and pesticides.
Method:
The synthesis method of 1-(4-bromo-2-chroophenyl) cyclopropan-1-amine is as follows:
1. First, bromine and chlorine are reacted to obtain 4-bromo-2-chlorobenzene.
2. Then, 4-bromo -2-chlorobenzene reacts with cyclopropane boronic acid substrate to generate 1-(4-bromo -2-chlorophenyl) cyclopropane through cyclopropanation reaction.
3. Finally, 1-(4-bromo-2-chlorophenyl) Cyclopropane is reacted with amine, and then reacted with hydrochloric acid to prepare 1-(4-bromo-2-chlorophenyl)cyclopropan-1-amine hydrochloride.
Safety Information:
- 1-(4-bromo-2-chlorophenyl)cyclopropan-1-amine should avoid contact with skin, eyes and respiratory tract during storage and handling.
-Use with appropriate protective equipment, such as lab gloves and glasses.
-Follow the safety procedures of the chemical laboratory during operation and handling.
-please read the security data form (SDS) provided by the supplier carefully for detailed security information.
Last Update：2024-04-09 21:01:54