1-(cyclopropylmethyl)piperazine - Names and Identifiers
1-(cyclopropylmethyl)piperazine - Physico-chemical Properties
Molecular Formula | C8H16N2
|
Molar Mass | 140.23 |
Density | 0.943 g/mL at 25 °C |
Boling Point | 68 °C/3.5 mmHg |
Flash Point | 171°F |
Vapor Presure | 0.213mmHg at 25°C |
pKa | 9.25±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.489 |
MDL | MFCD00872053 |
1-(cyclopropylmethyl)piperazine - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/39 -
|
UN IDs | UN 1993 / PGIII |
WGK Germany | 2 |
Hazard Note | Irritant |
1-(cyclopropylmethyl)piperazine - Introduction
1-(cyclopropylmethyl)piperazine is an organic compound with the chemical formula C10H18N2. It is a white crystalline solid, stable at room temperature. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-Melting point: 90-94 degrees Celsius
-Boiling point: 255 degrees Celsius
-Solubility: Soluble in water and some organic solvents, such as ethanol, ether, etc.
-Stability: stable at room temperature, but may react when encountering strong oxidants
Use:
-medical field: 1-(cyclopropylmethyl)piperazine is a regulator of neurotransmitters, used to treat anxiety, depression and other mental diseases. It can affect the chemical transmission of the nervous system, so as to achieve the effect of treatment.
-Research field: 1-(cyclopropylmethyl)piperazine is often used to study neurochemical transmission and the pathogenesis of nervous system-related diseases due to its regulatory effect on neurotransmitters.
Preparation Method:
The preparation method of 1-(cyclopropylmethyl)piperazine can be carried out by the following steps:
1. methylpiperazine is reacted with cyclopropyl haloalkane (such as cyclopropyl chloromethane) to generate 1-(cyclopropylmethyl)piperazine. The reaction is usually carried out under the protection of an inert gas, such as nitrogen, and at a suitable temperature.
2. The reaction product is crystallized, purified and dried to obtain pure 1-(cyclopropylmethyl)piperazine.
Safety Information:
- 1-(cyclopropylmethyl)piperazine is a chemical and should be used and handled in accordance with safe operating procedures.
-Wear appropriate personal protective equipment during use, including chemical safety glasses, gloves, and lab coats.
-Avoid inhalation, contact with skin and eyes, and avoid ingestion. In case of accidental contact, rinse the corresponding parts immediately with plenty of water and seek medical assistance if necessary.
-It should be stored in a sealed container, away from fire and oxidizing agents, and avoid prolonged exposure to the sun.
-Comply with local laws and regulations and properly dispose of waste from this compound. If necessary, consult or refer to the relevant safety data sheet (SDS).
Last Update:2024-04-09 21:04:16