1-苄基-2,5-吡咯烷羧酸二乙酯

1-苄基-2,5-吡咯烷羧酸二乙酯 - Names and Identifiers

Name	diethyl 1-benzylpyrrolidine-2,5-dicarboxylate
Synonyms	diethyl 1-benzylpyrrolidine-2,5-dicarboxylate 2,5-diethyl 1-benzylpyrrolidine-2,5-dicarboxylate 1-(phenylmethyl)pyrrolidine-2,5-dicarboxylic acid diethyl ester 2,5-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl)-, 2,5-diethyl ester 1-Benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine, {[2,5-Bis(ethoxycarbonyl)pyrrolidin-2-yl]methyl}benzene 1-Benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine, {[2,5-Bis(ethoxycarbonyl)pyrrolidin-1-yl]methyl}benzene
CAS	17740-40-8
InChI	InChI=1/C17H23NO4/c1-3-21-16(19)14-10-11-15(17(20)22-4-2)18(14)12-13-8-6-5-7-9-13/h5-9,14-15H,3-4,10-12H2,1-2H3

1-苄基-2,5-吡咯烷羧酸二乙酯 - Physico-chemical Properties

Molecular Formula	C17H23NO4
Molar Mass	305.37
Density	1.146g/cm³
Boling Point	381.3°C at 760 mmHg
Flash Point	184.4°C
Vapor Presure	5.14E-06mmHg at 25°C
pKa	5.83±0.60(Predicted)
Storage Condition	2-8°C
Refractive Index	1.53

1-苄基-2,5-吡咯烷羧酸二乙酯 - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

1-苄基-2,5-吡咯烷羧酸二乙酯 - Upstream Downstream Industry

Raw Materials	Diethyl meso-2,5-dibromoadipate Diethyl 2,5-dibromohexanedioate Benzylamine
Downstream Products	TERT-BUTYL 3-BENZYL-3,8-DIAZABICYCLO[3.2.1]OCTANE-8-CARBOXYLATE

1-苄基-2,5-吡咯烷羧酸二乙酯 - Introduction

diethyl 1-benzylpyrrolidine-2,5-dicarboxylate is an organic compound with the chemical formula C17H18N2O8, containing a benzyl group and two ethyl ester groups in the structure. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
diethyl 1-benzylpyrrolidine-2,5-dicarboxylate is a colorless to light yellow solid, which is soluble in organic solvents. It is relatively stable at room temperature, but may decompose at high temperatures.

Use:
diethyl 1-benzylpyrrolidine-2,5-dicarboxylate can be used as an intermediate in organic synthesis and medicinal chemistry. It can be used as a raw material for the synthesis of a variety of drugs and dyes, and can also be used to produce polymer compounds, such as polymers and resins.

Method:
A common method for synthesizing diethyl 1-benzylpyrrolidine-2,5-dicarboxylate is to react 2,5-pyrrolidine dicarboxylic acid with benzyl bromide, and then react with boric acid or nickel as a catalyst, it is esterified with ethanol to generate the target product.

Safety Information:
diethyl 1-benzylpyrrolidine-2,5-dicarboxylate is toxic and should be avoided by inhalation, ingestion and contact with skin. Appropriate protective measures should be taken during handling or use, such as wearing chemical protective gloves, glasses and protective clothing. If it comes into contact with skin or eyes, rinse immediately with plenty of water and seek medical attention. Avoid direct sunlight and high temperature when storing, and keep it sealed.

Last Update：2024-04-09 02:00:43