1-(2-chlorophenyl)-2-methyl-1-propanone

1-(2-chlorophenyl)-2-methyl-1-propanone - Names and Identifiers

Name	Cyclopropyl 2-thienyl ketone
Synonyms	Cyclopropyl 2-thieny 2-Thienoylcyclopropane Cyclopropyl -thienyl ketone Cyclopropyl 2-thienyl ketone Cyclopropyl 2-thyenyl ketone Cyclopropyl(2-thienyl)methanone Methanone, cyclopropyl-2-thienyl- Cyclopropyl-thiophen-2-ylmethanone cyclopropyl(thiophen-2-yl)methanone 1-(2-chlorophenyl)-2-methyl-1-propanone
CAS	6193-47-1
EINECS	228-247-1
InChI	InChI=1/C8H8OS/c9-8(6-3-4-6)7-2-1-5-10-7/h1-2,5-6H,3-4H2

1-(2-chlorophenyl)-2-methyl-1-propanone - Physico-chemical Properties

Molecular Formula	C8H8OS
Molar Mass	152.21
Density	1.17g/mLat 25°C(lit.)
Boling Point	120 °C / 3mmHg
Flash Point	198°F
Vapor Presure	0.0092mmHg at 25°C
Appearance	Liquid
Color	Colorless to Light yellow to Light orange
Storage Condition	Keep in dark place,Sealed in dry,2-8°C
Refractive Index	n20/D 1.584(lit.)
MDL	MFCD00005427

1-(2-chlorophenyl)-2-methyl-1-propanone - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
WGK Germany	3
HS Code	29349990

1-(2-chlorophenyl)-2-methyl-1-propanone - Introduction

Cyclopropyl 2-thienyl ketone is an organic compound with the chemical formula C9H8OS. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless liquid or solid
-Melting point: about -25 ℃
-Boiling point: about 236-240 ℃
-Density: about 1.22g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents

Use:
Cyclopropyl 2-thienyl ketone is often used as an intermediate and reagent in organic synthesis. Specific applications include:
-for the preparation of drugs
-Used as synthetic intermediates for pesticides and insecticides
-For organic synthesis reactions, such as acylation, substitution reactions, etc.

Preparation Method:
Cyclopropyl 2-thienyl ketone can be prepared by the following reaction pathways:
1. Cyclopropylamine and 2-chlorothiophene react to generate 2-thiophenyl cyclopropylamine.
2. 2-thiophenylcyclopropylamine is further treated with a ketonizing agent (such as sodium ketonate) to obtain the Cyclopropyl 2-thienyl ketone.

Safety Information:
Cyclopropyl 2-thienyl ketone is relatively safe under proper use and storage conditions. However, as an organic compound, it should be regarded as a potentially hazardous substance and needs to follow safe handling measures to protect individuals and the environment. When handling, avoid inhalation of vapors, contact with skin and eyes. At the same time, store it in a sealed container, away from fire and oxidizing agents. In case of accidental contact or misuse, seek medical help immediately. Be sure to consult the safety data form for the compound in detail before use and follow the relevant safety instructions.

Last Update：2024-04-09 21:11:58