1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-1,2,3,6-tetrahydropyrimidine-2-one
ICILIN
CAS: 36945-98-9
Molecular Formula: C16H13N3O4
1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-1,2,3,6-tetrahydropyrimidine-2-one - Names and Identifiers
1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-1,2,3,6-tetrahydropyrimidine-2-one - Physico-chemical Properties
| Molecular Formula | C16H13N3O4 |
| Molar Mass | 311.29 |
| Density | 1.415±0.06 g/cm3(Predicted) |
| Boling Point | 594.8±50.0 °C(Predicted) |
| Solubility | DMSO: 15mg/mL, soluble |
| Appearance | solid |
| Color | yellow |
| pKa | 9.94±0.35(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-1,2,3,6-tetrahydropyrimidine-2-one - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | UW7397500 |
1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-1,2,3,6-tetrahydropyrimidine-2-one - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.212 ml | 16.062 ml | 32.124 ml |
| 5 mM | 0.642 ml | 3.212 ml | 6.425 ml |
| 10 mM | 0.321 ml | 1.606 ml | 3.212 ml |
| 5 mM | 0.064 ml | 0.321 ml | 0.642 ml |
Last Update：2024-01-02 23:10:35
1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-1,2,3,6-tetrahydropyrimidine-2-one - Reference Information
| biological activity | Icilin (AG-3-5) is an agonist of the non-selective cation channel TRPM8, has anti-proliferative activity. Icilin activates only the current of wild-type TRPM8 and is Ca2-dependent. Icilin can induce G1 phase arrest of cell cycle in prostate cancer cells. |
Last Update：2024-04-09 21:11:58
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Spot supply
Product Name: ICILIN Visit Supplier Webpage Request for quotationCAS: 36945-98-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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