1-(Benzyloxycarbonyl)piperazine-2-carboxylic acid

1-(Benzyloxycarbonyl)piperazine-2-carboxylic acid - Names and Identifiers

Name	1-Cbz-Piperazine-2-Carboxylic Acid
Synonyms	1-Cbz-Piperazine-2-Carboxylic Acid 1-CBZ-PIPERAZINE-2-CARBOXYLIC ACID 1N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID 1N-Cbz-Piperazine-2-Carboxylic Acid Piperazine-1,2-Dicarboxylic Acid 1-Benzyl Ester PIPERAZINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER 1-(Benzyloxycarbonyl)piperazine-2-carboxylic acid 1-[(Benzyloxy)Carbonyl]Piperazine-2-Carboxylic Acid 1-phenylmethoxycarbonyl-2-piperazinecarboxylic acid 1-phenylmethoxycarbonylpiperazine-2-carboxylic acid 1,2-Piperazinedicarboxylic acid, 1-(phenylmethyl) ester
CAS	129365-24-8
InChI	InChI=1/C13H16N2O4/c16-12(17)11-8-14-6-7-15(11)13(18)19-9-10-4-2-1-3-5-10/h1-5,11,14H,6-9H2,(H,16,17)

1-(Benzyloxycarbonyl)piperazine-2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C13H16N2O4
Molar Mass	264.28
Density	1.294g/cm³
Boling Point	465.1°C at 760 mmHg
Flash Point	235.1°C
Vapor Presure	1.88E-09mmHg at 25°C
Storage Condition	2-8°C(protect from light)
Refractive Index	1.569

1-(Benzyloxycarbonyl)piperazine-2-carboxylic acid - Introduction

1-CBZ-piperazine -2-carboxylic acid is an organic compound whose chemical name is acid, or CBZ-PICA for short.

Nature:
1-CBZ-piperazine-2-carboxylic acid is a white crystalline solid, soluble in some organic solvents such as chloroform, methanol and ethanol. Its solubility in water is low.

Use:
1-CBZ-piperazine-2-carboxylic acid is mainly used as an intermediate in organic synthesis. It can be used to synthesize pharmaceutical intermediates and active substances, such as anticancer drugs, antipsychotic drugs and inhibitors.

Preparation Method:
1-CBZ-piperazine-2-carboxylic acid can be prepared by reacting CBZ-PICA-NHS (acid-N-hydroxysuccinimide ester) with sodium hydroxide followed by acidification.

Safety Information:
Regarding the safety of 1-CBZ-piperazine-2-carboxylic acid, it needs to be evaluated according to its specific use. However, in general, chemicals are dangerous, so the following precautions should be followed when using them:
1. avoid contact with skin and eyes, avoid inhalation or ingestion.
2. Wear appropriate personal protective equipment such as chemical protective gloves and goggles during operation.
3. Operate in a well-ventilated laboratory environment to avoid inhaling its vapors.
4. need to seal the container when stored, away from the fire and flammable materials.
5. Follow the correct waste disposal methods to avoid harm to the environment.

Before using any chemical, it is recommended to consult the relevant safety data sheets and operating manuals to ensure that the correct operating procedures are properly understood and followed.

Last Update：2024-04-09 21:54:55