1-(Bromomethyl)-2-chloro-4-methoxybenzene

1-(Bromomethyl)-2-chloro-4-methoxybenzene - Names and Identifiers

Name	2-Chloro-4-methoxybenzyl bromide
Synonyms	2-Chloro-4-methoxybenzyl bromide 4-methoxy-2-chlorobenzyl Bromide Bromomethyl-2-Chloro-4-Methoxybenzene 1-Bromomethyl-2-Chloro-4-Methoxybenzene 1-BROMOMETHYL-2-CHLORO-4-METHOXYBENZENE 1-(Bromomethyl)-2-chloro-4-methoxybenzene 4-(Bromomethyl)-3-chlorophenyl methyl ether benzene, 1-(bromomethyl)-2-chloro-4-methoxy- Benzene, 1-(bromomethyl)-2-chloro-4-methoxy-
CAS	54788-17-9
InChI	InChI=1/C8H8BrClO/c1-11-7-3-2-6(5-9)8(10)4-7/h2-4H,5H2,1H3

1-(Bromomethyl)-2-chloro-4-methoxybenzene - Physico-chemical Properties

Molecular Formula	C8H8BrClO
Molar Mass	235.51
Density	1.520±0.06 g/cm3(Predicted)
Melting Point	53-57 °C
Boling Point	275.6±25.0 °C(Predicted)
Flash Point	104℃
Vapor Presure	0.009mmHg at 25°C
Storage Condition	-20°C
Refractive Index	1.565
MDL	MFCD08445696

1-(Bromomethyl)-2-chloro-4-methoxybenzene - Risk and Safety

Risk Codes	R34 - Causes burns R25 - Toxic if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	1759
WGK Germany	3
Hazard Class	8
Packing Group	III

1-(Bromomethyl)-2-chloro-4-methoxybenzene - Introduction

bromide is an organic compound with the chemical formula C8H8BrClO. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid
-Boiling point: 170-172 ℃
-Molecular weight: 233.51g/mol
-Solubility: Soluble in organic solvents such as chloroform, ether and dimethyl sulfide

Use:
-bromide can be used as reagents and intermediates in organic synthesis
-It can be used to synthesize biologically active compounds, such as drugs, pesticides and dyes

Preparation Method:
The bromide can be synthesized by the following steps:
1. react 2-methoxybenzaldehyde with sodium sulfite to generate 2-methoxybenzyl alcohol.
2. react 2-methoxybenzyl alcohol with cuprous cyanide to generate 2-cyano -4-methoxybenzyl alcohol.
3. react 2-cyano -4-methoxybenzyl alcohol with cuprous chloride and cuprous bromide to generate 2-chloro -4-methoxybenzyl alcohol.
4. Finally, react 2-chloro-4-methoxybenzyl alcohol with hydrobromic acid to generate bromide.

Safety Information:
-bromide is an organic halogenated hydrocarbon and should be used with care.
-Avoid contact with skin, eyes and mucous membranes.
-Good ventilation and appropriate protective equipment such as gloves, face shield and goggles should be worn during use.
-When exposed to this compound, immediately rinse the affected area with plenty of water and seek medical help.

Last Update：2024-04-09 21:00:56