1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID

1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID - Names and Identifiers

Name	1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
Synonyms	1-(tert-Butyl)-5- carboxy-3-methyl-1H-pyrazole 2-tert-butyl-5-methyl-3-pyrazolecarboxylic acid 1-(TERT-BUTYL)-3-METHYLPYRAZOLE-5-CARBOXYLIC ACID 1-tert-Butyl-3-methyl-1H-pyrazole-5-carboxylic acid 1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 1-(tert-Butyl)-3-methyl-1H-pyrazole-5-carboxylic acid 1-(1,1-DIMETHYLETHYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLICACID 1H-Pyrazole-5-carboxylic acid, 1-(1,1-dimethylethyl)-3-methyl-
CAS	175277-09-5
InChI	InChI=1/C9H14N2O2/c1-6-5-7(8(12)13)11(10-6)9(2,3)4/h5H,1-4H3,(H,12,13)

1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID - Physico-chemical Properties

Molecular Formula	C9H14N2O2
Molar Mass	182.22
Density	1.13g/cm³
Melting Point	149 °C
Boling Point	313.9°C at 760 mmHg
Flash Point	143.7°C
Vapor Presure	0.000204mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.533

1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Irritant

1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID - Introduction

1-(TERT-BUTYL)-ACID, also known as TBTA(Tert-butyl-3-methyl-1H-pyrazole-5-carboxylic acid), is an organic compound.

Nature:
1-(TERT-BUTYL)-ACID is a solid with a white crystalline appearance. Its molecular formula is C10H15N3O2 and its relative molecular mass is 209.25g/mol. The compound is stable at room temperature.

Use:
1-(TERT-BUTYL)-ACID is often used as a coordination reagent, especially in coordination catalytic reactions play an important role. It can form stable complexes with metal ions, and is used in many organic synthesis reactions for catalytic cross-coupling, olefin cyclization, C- H activation, etc. In addition, it can also be used as a fluorescent probe for the detection of metal ions.

Method:
1-(TERT-BUTYL)-amino ACID can be prepared by the condensation reaction of pyrazole-5-carbaldehyde and tert-butyl carboxylic ACID. The reaction is generally carried out under basic conditions under an inert atmosphere.

Safety Information:
1-(TERT-BUTYL)-The toxicity of ACID is low, but it is still necessary to comply with regular laboratory safety procedures, avoid inhalation, skin contact and ingestion. Wear personal protective equipment such as chemical protective goggles, gloves and protective clothing during operation. If you feel unwell or take it by mistake, you should seek medical attention immediately.

Last Update：2024-04-10 22:29:15