1-(chloromethyl)-2,3,4,5-tetrafluorobenzene

1-(chloromethyl)-2,3,4,5-tetrafluorobenzene - Names and Identifiers

Name	4-Bromo-2-fluorobenzenesulfonyl chloride
Synonyms	4-Bromo-2-fluorobenzenesulfonyl chloride 2-FLUORO-4-BROMOBENZENESULFONYL CHLORIDE 4-BROMO-2-FLUOROBENZENESULFONYL CHLORIDE 4-BROMO-2-FLUOROBENZENESULPHONYL CHLORIDE 4-Bromo-2-fluorobenzenesulphonyl chloride 1-(chloromethyl)-2,3,4,5-tetrafluorobenzene 4-broMo-2-fluorobenzene-1-sulfonyl chloride
CAS	216159-03-4
InChI	InChI=1/C7H3ClF4/c8-2-3-1-4(9)6(11)7(12)5(3)10/h1H,2H2

1-(chloromethyl)-2,3,4,5-tetrafluorobenzene - Physico-chemical Properties

Molecular Formula	C6H3BrClFO2S
Molar Mass	273.51
Density	1.867±0.06 g/cm3(Predicted)
Melting Point	63-66 °C (lit.)
Boling Point	84°C 0,5mm
Flash Point	84°C/0.5mm
Solubility	soluble in Toluene
Vapor Presure	2.04mmHg at 25°C
Appearance	Solid
Color	White to Almost white
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Moisture Sensitive
Refractive Index	1.449
MDL	MFCD01090993

1-(chloromethyl)-2,3,4,5-tetrafluorobenzene - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3261 8/PG 2
WGK Germany	3
HS Code	29049090
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

1-(chloromethyl)-2,3,4,5-tetrafluorobenzene - Introduction

chloride is an organic compound with the chemical formula C6H3BrClFOS. The following is a description of the properties, uses, manufacturing methods and safety information of the compound:

Nature:
-Appearance: Colorless to slightly yellow crystalline solid
-Melting point: 69-72 degrees Celsius
-Boiling point: no clear boiling point, will decompose
-Density: 1.827g/cm3
-Solubility: Soluble in some organic solvents such as dimethylformamide and ethanol, insoluble in water.

Use:
-chloride is an important organic synthesis intermediate, which is widely used in the fields of pharmacy, pesticide and dye.
-It can be used to synthesize biologically active compounds, such as drugs, pesticides and dyes.
-The compound can also be used as a chlorinating agent for organic synthesis reactions.

Method:
A common preparation method is to react 4-Bromo-2-fluorobenzenesulfonic acid (fluorobenzenesulfonic acid) with thionyl chloride (sulfonyl chloride). The reaction conditions may use aluminum trichloride in thionyl chloride solution as a catalyst, and the reaction temperature is at room temperature.

Safety Information:
-chloride is an organic compound, which is corrosive and irritating. Appropriate laboratory safety measures, such as wearing chemical protective gloves and goggles, should be taken during use to ensure good ventilation.
-Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, flush immediately with plenty of water and seek medical help.
-Take care to prevent the substance from coming into contact with combustible substances to avoid the risk of fire or explosion.

Last Update：2024-04-09 15:17:55