1-(propan-2-yl)-1H-1,2,3-triazole-4-carboxylic acid
1-Isopropyl-1H-1,2,3-triazole-4-carboxylic acid
CAS: 1249780-66-2
Molecular Formula: C6H9N3O2
1-(propan-2-yl)-1H-1,2,3-triazole-4-carboxylic acid - Names and Identifiers
| Name | 1-Isopropyl-1H-1,2,3-triazole-4-carboxylic acid |
| Synonyms | 1-Isopropyl-1H-1,2,3-triazole-4-carboxylic acid 1-(propan-2-yl)-1H-1,2,3-triazole-4-carboxylic acid |
| CAS | 1249780-66-2 |
1-(propan-2-yl)-1H-1,2,3-triazole-4-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C6H9N3O2 |
| Molar Mass | 155.15 |
| Melting Point | 131 - 134oC |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Pale Green |
| Storage Condition | -20°C Freezer, Under inert atmosphere |
1-(propan-2-yl)-1H-1,2,3-triazole-4-carboxylic acid - Risk and Safety
| WGK Germany | 3 |
1-(propan-2-yl)-1H-1,2,3-triazole-4-carboxylic acid - Introduction
1-Isopropyl-1H-1,2,3-triazole-4-carboxylic acid (1-Isopropyl-1H-1,2,3-triazole-4-carboxylic acid) is an organic compound with the formula C6H8N4O2.
Properties: 1-Isopropyl-1H-1, 2,3-triazole-4-carboxylic acid is a colorless to slightly yellow crystalline solid, stable at room temperature. Its melting point is 175-177 degrees Celsius.
Application: 1-isopropyl-1H-1, 2,3-triazole-4-carboxylic acid is mainly used as an important starting material in organic synthesis. It can be used in the synthesis of drugs, ligands, catalysts and antibacterial agents and other compounds.
Preparation Method: The preparation of 1-isopropyl-1H-1, 2,3-triazole -4-carboxylic acid is generally accomplished by a three-step reaction. First, isopropoazidone is reacted with cyanoacetic acid to give an intermediate of 1-isopropyl-1H-1, 2,3-triazole-4-carboxylic acid. The intermediate is then converted to the target product by a hydrolysis reaction. Finally, the pure product is obtained from the solution using crystallization techniques.
Safety Information: 1-Isopropyl-1H-1, 2,3-triazole-4-carboxylic acid is not significantly hazardous under normal conditions of use. However, as a chemical, it can be irritating to the skin, eyes and respiratory system. If you come into contact with this substance, wash it with water immediately and seek medical help if necessary. Wear appropriate protective equipment, including gloves and goggles, during operation.
Properties: 1-Isopropyl-1H-1, 2,3-triazole-4-carboxylic acid is a colorless to slightly yellow crystalline solid, stable at room temperature. Its melting point is 175-177 degrees Celsius.
Application: 1-isopropyl-1H-1, 2,3-triazole-4-carboxylic acid is mainly used as an important starting material in organic synthesis. It can be used in the synthesis of drugs, ligands, catalysts and antibacterial agents and other compounds.
Preparation Method: The preparation of 1-isopropyl-1H-1, 2,3-triazole -4-carboxylic acid is generally accomplished by a three-step reaction. First, isopropoazidone is reacted with cyanoacetic acid to give an intermediate of 1-isopropyl-1H-1, 2,3-triazole-4-carboxylic acid. The intermediate is then converted to the target product by a hydrolysis reaction. Finally, the pure product is obtained from the solution using crystallization techniques.
Safety Information: 1-Isopropyl-1H-1, 2,3-triazole-4-carboxylic acid is not significantly hazardous under normal conditions of use. However, as a chemical, it can be irritating to the skin, eyes and respiratory system. If you come into contact with this substance, wash it with water immediately and seek medical help if necessary. Wear appropriate protective equipment, including gloves and goggles, during operation.
Last Update：2024-04-09 21:01:54
