1-Aminoindole
1H-Indol-1-amine
CAS: 53406-38-5
Molecular Formula: C8H8N2
1-Aminoindole - Names and Identifiers
| Name | 1H-Indol-1-amine |
| Synonyms | 1-Aminoindole Indol-1-ylaMine 1H-INDOL-1-AMINE 1H-Indol-1-amine |
| CAS | 53406-38-5 |
| InChI | InChI=1/C8H8N2/c9-10-6-5-7-3-1-2-4-8(7)10/h1-6H,9H2 |
1-Aminoindole - Physico-chemical Properties
| Molecular Formula | C8H8N2 |
| Molar Mass | 132.16 |
| Density | 1.18±0.1 g/cm3(Predicted) |
| Melting Point | 40 °C |
| Boling Point | 296.2±23.0 °C(Predicted) |
| Flash Point | 132.9°C |
| Vapor Presure | 0.00146mmHg at 25°C |
| pKa | 7.05±0.70(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.638 |
1-Aminoindole - Introduction
1H-Indol-1-amine(1H-Indol-1-amine) is an organic compound with the chemical formula C8H8N2, which has an indole ring and an amine group in its structure. The following is information on the properties, use, preparation and safety of the compound:
Nature:
1H-Indol-1-amine is a colorless to light yellow solid, insoluble in water at room temperature, but soluble in organic solvents such as ethanol and dichloromethane. It can be identified by melting point, boiling point and mass spectrometry.
Use:
1H-Indol-1-amine is an important organic synthesis intermediate, commonly used in the preparation of various drugs, pesticides and dyes and other compounds. It can also be used as a reagent for biochemical research and for the synthesis of specific classes of compounds, such as indole alkaloids.
Preparation Method:
There are various methods for preparing 1H-Indol-1-amine. One common method is by the redox reaction of indole. First, indole reacts with silver nitrate or nitrate to form indole N-oxide, which is then reduced to give 1H-Indol-1-amine. In addition, it can also be prepared by other synthetic methods, such as aminolysis, reduction of diazo compounds and alkylation of indole rings.
Safety Information:
1H-Indol-1-amine is generally considered a relatively safe compound under routine laboratory operating conditions. However, it may have an irritating effect on the eyes, skin and respiratory system. Wear appropriate personal protective equipment, such as lab gloves and protective glasses. Care should be taken when handling or storing compounds to avoid dust or contact with skin, and to avoid inhalation of vapors or dust. In the event of accidental exposure or ingestion, seek medical attention immediately and bring information about the compound.
Nature:
1H-Indol-1-amine is a colorless to light yellow solid, insoluble in water at room temperature, but soluble in organic solvents such as ethanol and dichloromethane. It can be identified by melting point, boiling point and mass spectrometry.
Use:
1H-Indol-1-amine is an important organic synthesis intermediate, commonly used in the preparation of various drugs, pesticides and dyes and other compounds. It can also be used as a reagent for biochemical research and for the synthesis of specific classes of compounds, such as indole alkaloids.
Preparation Method:
There are various methods for preparing 1H-Indol-1-amine. One common method is by the redox reaction of indole. First, indole reacts with silver nitrate or nitrate to form indole N-oxide, which is then reduced to give 1H-Indol-1-amine. In addition, it can also be prepared by other synthetic methods, such as aminolysis, reduction of diazo compounds and alkylation of indole rings.
Safety Information:
1H-Indol-1-amine is generally considered a relatively safe compound under routine laboratory operating conditions. However, it may have an irritating effect on the eyes, skin and respiratory system. Wear appropriate personal protective equipment, such as lab gloves and protective glasses. Care should be taken when handling or storing compounds to avoid dust or contact with skin, and to avoid inhalation of vapors or dust. In the event of accidental exposure or ingestion, seek medical attention immediately and bring information about the compound.
Last Update：2024-04-09 21:01:54
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CAS: 53406-38-5
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CAS: 53406-38-5
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Mobile: 18021002903
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