1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE

1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE - Names and Identifiers

Name	1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE
Synonyms	1-Boc-4-(hydroxymethyl)piperidin-4-ol 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE tert-butyl 4-hydroxy-4-(hydroxymethyl)piperidine-1-carboxylate 4-Hydroxy-4-hydroxyMethylpiperidine-1-carboxylic acid tert-butyl ester 1-Piperidinecarboxylic acid, 4-hydroxy-4-(hydroxymethyl)-, 1,1-dimethylethyl ester
CAS	389889-80-9
EINECS	200-589-5

1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE - Physico-chemical Properties

Molecular Formula	C11H21NO4
Molar Mass	231.29
Density	1.164±0.06 g/cm3(Predicted)
Boling Point	350.9±27.0 °C(Predicted)
pKa	14.06±0.20(Predicted)
Storage Condition	2-8℃

1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE - Introduction

1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE is an organic compound with the molecular formula C13H23NO4, commonly abbreviated as Boc-PIP-OH. It is a solid, colorless or yellowish crystal.

Nature:
1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE is an amino alcohol compound containing two hydroxyl groups and a Methyl hydroxide functional group. Its hydroxyl group can undergo esterification, acylation and nucleophilic substitution reactions.

Use:
1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE is commonly used in the field of organic synthesis. As a chemical reagent, it is often used in the synthesis of other compounds, intermediates and active substances, such as drugs, ligands and polymers. It can be used as a protecting group or a reaction intermediate, and has important applications in the synthesis of peptides and drugs.

Method:
1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE is usually synthesized by protecting 4-hydroxy-4-hydroxymethylpiperidine. A commonly used protecting group is tert-butoxycarbonyl (Boc). Such reactions are generally carried out at room temperature, using suitable reagents and solvents, and generally require longer times to obtain higher yields.

Safety Information:
No toxicity data are currently available for 1-BOC-4-HYDROXY-4-(HYDROXYMETHYL)-PIPERIDINE. However, as an organic compound, it can be irritating to the skin, eyes and respiratory tract. Appropriate protective measures, such as gloves, safety glasses and protective masks, should be taken during handling and use. Avoid inhalation, ingestion or contact with skin. Before operation, the relevant hazardous matters and safe operation guidelines should be fully understood and observed. Keep under correct storage conditions and away from fire and oxidizing agents.

Last Update：2024-04-09 20:45:29