1-Boc-2-ethylpiperazine

1-Boc-2-ethylpiperazine - Names and Identifiers

Name	1-N-Boc-2-ethylpiperazine
Synonyms	N-Boc-2-ethylpiperazine 1-Boc-2-ethylpiperazine N-1-Boc-2-ethyl-piperazi 1-Boc-2-ethyl-piperazine 1-N-Boc-2-ethylpiperazine 1-N-Boc-2-ethylpiperizine N-1-Boc-2-ethyl-piperazine N-1-BOC-2-ETHYL PIPERAZINE 1-N-tert-Butoxycarbonyl-2-ethylpiperazine tert-butyl 2-ethylpiperazine-1-carboxylate 1-N-(TERT-BUTOXYCARBONYL)-2-ETHYL-PIPERAZINE 2-ETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS	393781-71-0
InChI	InChI=1/C11H22N2O2/c1-5-9-8-12-6-7-13(9)10(14)15-11(2,3)4/h9,12H,5-8H2,1-4H3

1-Boc-2-ethylpiperazine - Physico-chemical Properties

Molecular Formula	C11H22N2O2
Molar Mass	214.3
Density	0.981±0.06 g/cm3(Predicted)
Boling Point	286.7±15.0 °C(Predicted)
Flash Point	127.2°C
Vapor Presure	0.0026mmHg at 25°C
pKa	8.49±0.40(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.457

1-Boc-2-ethylpiperazine - Introduction

1-N-Boc-2-ethylpiperazine is an organic compound with the chemical formula C12H24N2O2. It is a solid with a blue crystal structure.

1-N-Boc-2-ethylpiperazine is commonly used as a reagent and ligand in organic synthesis. It can be used to synthesize precursor compounds of biologically active molecules, such as drugs and pesticides. Because of its basicity and nucleophilicity, it can be used for the introduction and removal of amino protecting groups, as well as redox reactions and alkylation reactions in organic synthesis.

The method for preparing 1-N-Boc-2-ethylpiperazine can be carried out by the following steps. First, 2-ethylpiperazine is reacted with N-tert-butoxycarbene (using tert-butyldimethoxysilane as a reactant) to produce N-tert-butoxycarbonyl-2-ethylpiperazine. It was then reduced to 1-N-Boc-2-ethylpiperazine using hydrochloric acid.

Regarding safety information, 1-N-Boc-2-ethylpiperazine is relatively safe under proper handling and storage conditions. As an organic compound, it may have an irritating effect on the skin, eyes and respiratory tract. Therefore, suitable personal protective equipment such as gloves, goggles and masks should be worn during use. In addition, it should be properly kept and avoid mixing with oxidants, acids, alkalis and other chemical substances. If necessary, it is recommended to refer to the relevant safety data form or consult a professional for more detailed and accurate safety information.

Last Update：2024-04-09 21:04:16