1-Boc-3-azetidineacetic acid methyl ester

1-Boc-3-azetidineacetic acid methyl ester - Names and Identifiers

Name	3-Azetidineaceticacid, 1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
Synonyms	Methyl 1-Boc-3-azetidinea... Methyl 1-Boc-3-azetidineacetate Methyl 1-Boc-azetidine-3-acetate 1-Boc-3-(2-Methoxy-2-oxoethyl)azetidine 1-Boc-3-azetidineacetic acid methyl ester tert-Butyl3-(2-methoxy-2-oxoethyl)azetidine-1-carboxylate tert-butyl 3-(2-methoxy-2-oxoethyl)azetidine-1-carboxylate Methyl 2-{1-[(tert-butyl)oxycarbonyl]azetidin-3-yl}acetate TERT-BUTYL 3-((METHOXYCARBONYL)METHYL) AZETIDINE-1-CARBOXYLATE 3-Azetidineaceticacid, 1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester 3-Azetidineacetic acid, 1-[(1,1-diMethylethoxy)carbonyl]-, Methyl ester
CAS	497160-14-2

1-Boc-3-azetidineacetic acid methyl ester - Physico-chemical Properties

Molecular Formula	C11H19NO4
Molar Mass	229.27
Density	1.108±0.06 g/cm3(Predicted)
Boling Point	285.8±13.0 °C(Predicted)
pKa	-2.28±0.40(Predicted)
Storage Condition	2-8°C

1-Boc-3-azetidineacetic acid methyl ester - Introduction

3-Azetidineaceticacid, 1-[(1,1-dimenthylethoxy) carbonyl]-, methyl ester is an organic compound with the chemical formula C10H17NO4. It is a solid with low solubility. Its structure contains a 3-azetidine ring, an acetoxy group and a Boc(tert-butyloxycarbonyl) protecting group. Boc group is a common amino protecting group, can protect the amine group does not react, can be removed under suitable conditions.

3-Azetidineaceticacid, 1-[(1,1-dimenthylethoxy) carbonyl]-, methyl ester is often used as an intermediate in organic synthesis. It can be used in the synthesis of various organic compounds, especially the synthesis of heterocyclic compounds. It also has important applications in the field of medicine, and is used to prepare drugs and pharmaceutical intermediates.

3-Azetidineaceticacid, 1-[(1,1-dimenthylethoxy) carbonyl]-, methyl ester is usually prepared by reacting 3-azetidine with methyl acetate, and then adding Boc-Cl (or Boc2O) to introduce the protecting group. The reaction conditions generally need to be carried out under an inert atmosphere and using a suitable solvent and catalyst.

Regarding safety information, 3-Azetidineaceticacid, 1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester is an organic compound with potential danger. It should be operated in a laboratory environment, and users need to understand and follow the appropriate safe operating procedures. It may have irritating effects on the eyes, skin and respiratory system, so appropriate protective measures such as wearing protective glasses, gloves and protective masks are required. At the same time, it should be kept away from fire and oxidant during storage and handling to avoid harmful gases.

Last Update：2024-04-09 21:11:58