1-Cbz-[1,4]diazepan-5-one
1-Cbz-[1,4]diazepan-5-one
CAS: 18158-16-2
Molecular Formula: C13H16N2O3
1-Cbz-[1,4]diazepan-5-one - Names and Identifiers
| Name | 1-Cbz-[1,4]diazepan-5-one |
| Synonyms | 1-Cbz-[1,4]diazepan-5-one Benzyl 5-Oxo-1,4-diazepane-1-carboxylate Benzyl 5-Oxo-1,4-diazepane-1-carboxylate 5-Oxo-[1,4]diazepane-1-carboxylic acid benzyl ester 1H-1,4-Diazepine-1-carboxylic acid, hexahydro-5-oxo-, phenylmethyl ester |
| CAS | 18158-16-2 |
| InChI | InChI=1/C13H16N2O3/c16-12-6-8-15(9-7-14-12)13(17)18-10-11-4-2-1-3-5-11/h1-5H,6-10H2,(H,14,16) |
1-Cbz-[1,4]diazepan-5-one - Physico-chemical Properties
| Molecular Formula | C13H16N2O3 |
| Molar Mass | 248.28 |
| Density | 1.204±0.06 g/cm3(Predicted) |
| Melting Point | 110-112 °C |
| Boling Point | 468.7±45.0 °C(Predicted) |
| Flash Point | 237.3°C |
| Vapor Presure | 5.84E-09mmHg at 25°C |
| pKa | 16.05±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.548 |
1-Cbz-[1,4]diazepan-5-one - Introduction
1-Cbz-[1,4]diazepan-5-one, also known as Cbz-ghk-5-ketone, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
1-Cbz-[1,4]diazepan-5-one is a solid compound with common physical properties including melting point, boiling point and molecular formula. Its molecular formula is C15H19N3O2 and its molecular weight is 273.33g/mol. It is a white crystalline solid with good solubility, soluble in organic solvents such as dichloromethane and ethanol.
Use:
1-Cbz-[1,4]diazepan-5-one have important applications in organic synthesis. It is often used as a protecting group in the synthesis of amino acids and peptides to protect amino groups in amino acids or amino acid residues. In addition, it can also be used in the synthesis of compounds with similar structures.
Method:
1-Cbz-[1,4]diazepan-5-one is prepared by a variety of methods. Common methods include the compound 1-Cbz-[1,4] diazepane (Cbz-ghk) reaction with Iodo ketone (I2) gives 1-Cbz-[1,4]diazepan-5-one. The specific preparation method can refer to the relevant organic synthesis literature.
Safety Information:
1-Cbz-[1,4]diazepan-5-one are generally relatively safe under correct operation. However, it can be irritating to the skin, eyes and respiratory system, so it is necessary to wear appropriate personal protective equipment, such as safety glasses, protective gloves and breathing masks. In addition, in order to avoid inhaling its dust or solution, it should be carried out in a well-ventilated environment. During use and storage, the relevant safety procedures shall be observed.
Nature:
1-Cbz-[1,4]diazepan-5-one is a solid compound with common physical properties including melting point, boiling point and molecular formula. Its molecular formula is C15H19N3O2 and its molecular weight is 273.33g/mol. It is a white crystalline solid with good solubility, soluble in organic solvents such as dichloromethane and ethanol.
Use:
1-Cbz-[1,4]diazepan-5-one have important applications in organic synthesis. It is often used as a protecting group in the synthesis of amino acids and peptides to protect amino groups in amino acids or amino acid residues. In addition, it can also be used in the synthesis of compounds with similar structures.
Method:
1-Cbz-[1,4]diazepan-5-one is prepared by a variety of methods. Common methods include the compound 1-Cbz-[1,4] diazepane (Cbz-ghk) reaction with Iodo ketone (I2) gives 1-Cbz-[1,4]diazepan-5-one. The specific preparation method can refer to the relevant organic synthesis literature.
Safety Information:
1-Cbz-[1,4]diazepan-5-one are generally relatively safe under correct operation. However, it can be irritating to the skin, eyes and respiratory system, so it is necessary to wear appropriate personal protective equipment, such as safety glasses, protective gloves and breathing masks. In addition, in order to avoid inhaling its dust or solution, it should be carried out in a well-ventilated environment. During use and storage, the relevant safety procedures shall be observed.
Last Update：2024-04-10 22:29:15
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CAS: 18158-16-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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