1-Methyl 6-oxo-1,6-dihydro-3-pyridinecarboxamide
1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
CAS: 701-44-0
Molecular Formula: C7H8N2O2
1-Methyl 6-oxo-1,6-dihydro-3-pyridinecarboxamide - Names and Identifiers
| Name | 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide |
| Synonyms | N'-methyl-2-pyridone-5-carboxamide N1-Methyl-2-pyridone-5-carboxamide 1-methyl-6-oxo-pyridine-3-carboxamide 1-Methyl-6-oxo-1,6-dihydronicotinamide 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide 1-Methyl 6-oxo-1,6-dihydro-3-pyridinecarboxamide 1,6-Dihydro-1-methyl-6-oxo-3-pyridinecarboxamide N-Methyl-2-pyridone-5-carboxaMide (NedifloraMide) 3-Pyridinecarboxamide, 1,6-dihydro-1-methyl-6-oxo- 3-pyridinecarboxamide, 1,6-dihydro-1-methyl-6-oxo- |
| CAS | 701-44-0 |
| InChI | InChI=1/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11) |
1-Methyl 6-oxo-1,6-dihydro-3-pyridinecarboxamide - Physico-chemical Properties
| Molecular Formula | C7H8N2O2 |
| Molar Mass | 152.15 |
| Density | 1.300±0.06 g/cm3(Predicted) |
| Melting Point | 202-207°C (dec.) |
| Boling Point | 396.7±42.0 °C(Predicted) |
| Flash Point | 193.7°C |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| Vapor Presure | 1.68E-06mmHg at 25°C |
| Appearance | Solid |
| Color | White to Light Brown |
| pKa | 14.46±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.576 |
| In vitro study | Nudifloramide is a more powerful inhibitor of PARP-1 than nicotinamide. |
1-Methyl 6-oxo-1,6-dihydro-3-pyridinecarboxamide - Reference Information
| biological activity | Nudifloramide (2PY) is one of the end products of Nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibited PARP-1 activity in vitro. |
Last Update：2024-04-09 21:54:55
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