1-Methylpiperdin-4-ylmagnesium chloride
1-Methylpiperdin-4-ylmagnesium chloride
CAS: 63463-36-5
Molecular Formula: C6H12ClMgN
1-Methylpiperdin-4-ylmagnesium chloride - Names and Identifiers
1-Methylpiperdin-4-ylmagnesium chloride - Physico-chemical Properties
| Molecular Formula | C6H12ClMgN |
| Molar Mass | 157.92 |
1-Methylpiperdin-4-ylmagnesium chloride - Introduction
chloride is an important organometallic reagent with a chemical formula of C6H12ClMgN and a molecular weight of 149.87g/mol. It is a metal derivative of the organic compound methylpiperidine, and has a structure in which the nitrogen atom on the piperidine ring is replaced by a magnesium ion.
The Grignard reagent reaction chloride is commonly used in organic synthesis. It can be used as a strong reducing agent, reducing carbonyl to alcohol or enol in organic synthesis. It can also react with carbonates to produce compounds with unique structures, such as β-aminoalcohols and enones. In addition, it can also be used to generate other organometallic reagents, such as zinc reagents and copper reagents.
preparation of the Grignard reagent reaction method is usually used chloride. Piperidine is first reacted with methylmagnesium chloride in ether or tetrahydrofuran solvent to produce 1-methylpiperidin-4-yl chloride. Then, the reaction mixture is mixed with a certain amount of magnesium powder, heated to reflux, and the Grignard reagent reaction is carried out to generate calcium chloride.
The chloride is a combustible and should be kept away from fire and high temperatures. Use the need to take good ventilation measures, avoid inhalation or contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help. Avoid contact with oxidizing agents or water during handling and storage to prevent possible dangerous reactions. It should be stored in a dry, cool place, away from fire and incompatible substances.
The Grignard reagent reaction chloride is commonly used in organic synthesis. It can be used as a strong reducing agent, reducing carbonyl to alcohol or enol in organic synthesis. It can also react with carbonates to produce compounds with unique structures, such as β-aminoalcohols and enones. In addition, it can also be used to generate other organometallic reagents, such as zinc reagents and copper reagents.
preparation of the Grignard reagent reaction method is usually used chloride. Piperidine is first reacted with methylmagnesium chloride in ether or tetrahydrofuran solvent to produce 1-methylpiperidin-4-yl chloride. Then, the reaction mixture is mixed with a certain amount of magnesium powder, heated to reflux, and the Grignard reagent reaction is carried out to generate calcium chloride.
The chloride is a combustible and should be kept away from fire and high temperatures. Use the need to take good ventilation measures, avoid inhalation or contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help. Avoid contact with oxidizing agents or water during handling and storage to prevent possible dangerous reactions. It should be stored in a dry, cool place, away from fire and incompatible substances.
Last Update：2024-04-10 22:29:15
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Product Name: 1-Methylpiperdin-4-ylmagnesium chloride Request for quotationCAS: 63463-36-5
Tel: 15001012717
Email: biz5@infsci.com
Mobile: 15001012717
QQ: 3007471201
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