1-Pyrrolidineacetamide, 2-methyl-5-oxo-3-phenyl-
(Rac)-E1R
CAS: 787623-60-3
Molecular Formula: C13H16N2O2
1-Pyrrolidineacetamide, 2-methyl-5-oxo-3-phenyl- - Names and Identifiers
1-Pyrrolidineacetamide, 2-methyl-5-oxo-3-phenyl- - Physico-chemical Properties
| Molecular Formula | C13H16N2O2 |
| Molar Mass | 232.28 |
| Density | 1.168±0.06 g/cm3(Predicted) |
| Boling Point | 480.0±45.0 °C(Predicted) |
| pKa | 15.67±0.40(Predicted) |
| In vitro study | Sigma-1 receptor plays an important role in neuronal plasticity, a process implicated in the pathophysiology of neuropsychiatric diseases, such as Alzheimer’s disease, major depressive disorders, and schizophrenia. |
1-Pyrrolidineacetamide, 2-methyl-5-oxo-3-phenyl- - References
| biological activity | (Rac)-E1R (Compound 2) is the racemate of E1R. (Rac)-E1R is a positive allosteric modulator of sigma-1 receptors (Sig1R PAM), which can be used in the study of cognitive and memory disorders. |
Last Update：2024-04-10 22:29:15
