1-Tert-Butoxycarbonylamino-Cyclobutanecarboxylic Acid

1-Tert-Butoxycarbonylamino-Cyclobutanecarboxylic Acid - Names and Identifiers

Name	N-Boc-1-aminocyclobutanecarboxylic acid
Synonyms	Boc-Ac4C-Oh 1-(BOC-AMINO)CYCLOBUTANECARBOXYLIC ACID 1-(Boc-Amino)Cyclobutanecarboxylic Acid N-Boc-1-aminocyclobutanecarboxylic acid N-BOC-1-AMINOCYCLOBUTANE CARBOXYLIC ACID 1-N-BOC-AMINO-CYCLOBUTANE CARBOXYLIC ACID 1-N-Boc-Amino-Cyclobutane Carboxylic Acid 1-Aminocyclobutyl-1-Carboxylic Acid, N-Boc Protected 1-AMINOCYCLOBUTYL-1-CARBOXYLIC ACID, N-BOC PROTECTED 1-[(tert-butoxycarbonyl)amino]cyclobutanecarboxylate 1-Tert-Butoxycarbonylamino-Cyclobutanecarboxylic Acid 1-TERT-BUTOXYCARBONYLAMINO-CYCLOBUTANECARBOXYLIC ACID 1-Aminocyclobutane-1-carboxylic acid, N-BOC protected 1-(T-Butyloxycarbonyl-Amino)-Cyclobutyl-1-Carboxylic Acid 1-(TERT-BUTYLOXYCARBONYL-AMINO)-CYCLOBUTYL-1-CARBOXYLIC ACID 1-(Tert-Butyloxycarbonyl-Amino)-Cyclobutyl-1-Carboxylic Acid
CAS	120728-10-1
InChI	InChI=1/C10H17NO4/c1-9(2,3)15-8(14)11-10(7(12)13)5-4-6-10/h4-6H2,1-3H3,(H,11,14)(H,12,13)/p-1
InChIKey	ROVVUKFHORPDSM-UHFFFAOYSA-N

1-Tert-Butoxycarbonylamino-Cyclobutanecarboxylic Acid - Physico-chemical Properties

Molecular Formula	C10H17NO4
Molar Mass	215.25
Density	1.18±0.1 g/cm3(Predicted)
Melting Point	129-133°C(lit.)
Boling Point	362.1±21.0 °C(Predicted)
Flash Point	172.8°C
Solubility	soluble in Methanol
Vapor Presure	3.16E-06mmHg at 25°C
Appearance	Solid
Color	White to light brown
BRN	7994003
pKa	4.14±0.20(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
MDL	MFCD02682623
Physical and Chemical Properties	Storage Conditions: 2-8 ℃ WGK Germany:3

1-Tert-Butoxycarbonylamino-Cyclobutanecarboxylic Acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
Safety Description	36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29242990
Hazard Class	IRRITANT

1-Tert-Butoxycarbonylamino-Cyclobutanecarboxylic Acid - Introduction

Boc-1-Aminocyclobutanecarboxylic acid is an organic compound with the formula Boc-NH-(CH2)3-COOH. It has the following properties:

1. physical properties: Boc-1-aminocyclobutane carboxylic acid is a colorless to pale yellow solid with a special odor. It is stable at room temperature and soluble in some organic solvents (such as chloroform, methanol, etc.).

2. chemical properties: Boc-1-aminocyclobutane carboxylic acid is a carboxylic acid compounds, acidic, can react with alkali. It is a compound that can be reduced and is also reactive for electrophilic substitution reactions.

The main use of Boc-1-aminocyclobutane carboxylic acid is as a protecting group in organic synthesis. It can protect the amino group in the process of chemical reaction and prevent the amino group from being affected by unnecessary reaction. In organic synthesis, it is often used as an intermediate in the synthesis of peptides, drugs and other organic molecules.

The method for producing Boc-1-aminocyclobutanecarboxylic acid can be obtained by reacting 1-aminocyclobutanecarboxylic acid with a substrate Boc-Cl. The reaction process generally requires the presence of organic solvents and bases, and the reaction conditions need to control the temperature and reaction time.

Regarding safety information, Boc-1-aminocyclobutane carboxylic acid is an organic substance and requires attention to the safety of use and storage. It may be irritating to the skin, eyes and respiratory system, so wear appropriate protective equipment (such as gloves, goggles and masks) during operation. In addition, care should be taken to avoid contact with oxidants and to ensure that the operation is carried out in a well-ventilated place. If accidental contact, should immediately rinse with water, and timely medical treatment.

Last Update：2024-04-09 20:52:54